Journal article
Homonymous Ganglion Cell Layer Thinning After Isolated Occipital Lesion: Macular OCT Demonstrates Transsynaptic Retrograde Retinal Degeneration
Journal of neuro-ophthalmology, Vol.35(2), pp.112-116
06/2015
DOI: 10.1097/WNO.0000000000000182
PMID: 25285723
Abstract
A 48-year-old man was examined 24 months after medial and surgical treatment of an isolated well-circumscribed right occipital lobe abscess. An asymptomatic residual left homonymous inferior scotoma was present. Fundus examination revealed temporal pallor of both optic discs, and optical coherence tomography (OCT) revealed mild temporal loss of retinal nerve fiber layer in both eyes. No relative afferent pupillary defect was present. Assessment of the retinal ganglion cell layer demonstrated homonymous thinning in a pattern corresponding to the homonymous visual field loss. There were no abnormalities of the lateral geniculate nuclei or optic tracts on review of the initial brain computed tomography and follow-up magnetic resonance imaging. We believe our patient showed evidence of transsynaptic retrograde degeneration after an isolated right occipital lobe lesion, and the homonymous neuronal loss was detected on OCT by assessing the retinal ganglion cell layer.
Details
- Title: Subtitle
- Homonymous Ganglion Cell Layer Thinning After Isolated Occipital Lesion: Macular OCT Demonstrates Transsynaptic Retrograde Retinal Degeneration
- Creators
- Paolo G Meier - University of LausannePhilippe MaederRandy H KardonFrançois-Xavier Borruat
- Resource Type
- Journal article
- Publication Details
- Journal of neuro-ophthalmology, Vol.35(2), pp.112-116
- DOI
- 10.1097/WNO.0000000000000182
- PMID
- 25285723
- NLM abbreviation
- J Neuroophthalmol
- ISSN
- 1070-8022
- eISSN
- 1536-5166
- Publisher
- United States
- Language
- English
- Date published
- 06/2015
- Academic Unit
- Iowa Neuroscience Institute; Ophthalmology and Visual Sciences
- Record Identifier
- 9983980065202771
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