Journal article
Homozygosity Mapping Using Pooled DNA
Current Protocols in Human Genetics, Vol.13(1), pp.1.11.1-1.11.21
05/1997
DOI: 10.1002/0471142905.hg0111s13
PMID: 18428233
Abstract
Genomic screening is a common and popular method for localizing human disease genes. Genotyping each individual sample can be a laborintensive and expensive process. This unit describes the technique of pooling DNA from many related affected individuals, genotyping the resulting pools, and scoring the results. This technique can greatly reduce the effort required to screen for genetic linkage and is particularly useful when applied to inbred populations. The unit includes a table showing a pool of human STRP markers developed by the Cooperative Human Linkage Center.
Details
- Title: Subtitle
- Homozygosity Mapping Using Pooled DNA
- Creators
- Val C Sheffield - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Current Protocols in Human Genetics, Vol.13(1), pp.1.11.1-1.11.21
- DOI
- 10.1002/0471142905.hg0111s13
- PMID
- 18428233
- ISSN
- 1934-8266
- eISSN
- 1934-8258
- Number of pages
- 21
- Language
- English
- Date published
- 05/1997
- Academic Unit
- Stead Family Department of Pediatrics; Iowa Neuroscience Institute; Medical Genetics and Genomics; Ophthalmology and Visual Sciences
- Record Identifier
- 9984065391002771
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