Journal article
Hospital Transmission of Community-Acquired Methicillin-Resistant Staphylococcus aureus among Postpartum Women
Clinical infectious diseases, Vol.37(10), pp.1313-1319
11/15/2003
DOI: 10.1086/379022
PMID: 14583864
Abstract
Infections caused by community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) are being increasingly observed in patients who lack traditional risk factors. We described 8 postpartum women who developed skin and soft-tissue infections caused by MRSA at a mean time of 23 days (range, 4-73 days) after delivery. Infections included 4 cases of mastitis (3 of which progressed to breast abscess), a postoperative wound infection, cellulitis, and pustulosis. The outbreak strains were compared with the prototype CA-MRSA strain MW2 and found to be indistinguishable by pulsed-field gel electrophoresis. All were spa type 131, all contained the staphylococcal chromosomal cassette mec type IV, and all expressed Panton-Valentine leukocidin and staphylococcal enterotoxins C and H. The route of transmission was not discovered: the results of surveillance cultures of samples obtained from employees of the hospital, the hospital environment, and newborns were negative for the outbreak strain. We report that MW2, which was previously limited to the midwestern United States, has spread to the northeastern United States and has become a health care-associated pathogen.
Details
- Title: Subtitle
- Hospital Transmission of Community-Acquired Methicillin-Resistant Staphylococcus aureus among Postpartum Women
- Creators
- Lisa Saiman - Departments of PediatricsMary O Keefe - Department of Epidemiology, New York-Presbyterian Medical CenterPhilip L Graham - Departments of PediatricsFann Wu - PathologyBattouli Saïd Salim - Public Health Research InstituteBarry Kreiswirth - Public Health Research InstituteAnita LaSala - Obstetrics and Gynecology, Columbia UniversityPatrick M Schlievert - Department of Microbiology, University of MinnesotaPhyllis Della Latta - Pathology
- Resource Type
- Journal article
- Publication Details
- Clinical infectious diseases, Vol.37(10), pp.1313-1319
- Publisher
- The University of Chicago Press
- DOI
- 10.1086/379022
- PMID
- 14583864
- ISSN
- 1058-4838
- eISSN
- 1537-6591
- Language
- English
- Date published
- 11/15/2003
- Academic Unit
- Microbiology and Immunology; Internal Medicine
- Record Identifier
- 9984001128502771
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