Hospitalizations for invasive pneumococcal disease among human immunodeficiency virus-1 infected children, adolescents and young adults in the United States in the era of highly active antiretroviral therapy and the conjugate pneumococcal vaccine

Athena P Kourtis; Sascha Ellington; Pooja Bansil; Denise J Jamieson; Samuel F Posner

doi:10.1097/INF.0b013e3181cfb65f

Back

Hospitalizations for invasive pneumococcal disease among human immunodeficiency virus-1 infected children, adolescents and young adults in the United States in the era of highly active antiretroviral therapy and the conjugate pneumococcal vaccine

Journal article

Open access

Peer reviewed

Hospitalizations for invasive pneumococcal disease among human immunodeficiency virus-1 infected children, adolescents and young adults in the United States in the era of highly active antiretroviral therapy and the conjugate pneumococcal vaccine

Athena P Kourtis, Sascha Ellington, Pooja Bansil, Denise J Jamieson and Samuel F Posner

The Pediatric infectious disease journal, Vol.29(6), pp.561-563

06/2010

DOI: 10.1097/INF.0b013e3181cfb65f

PMID: 20094005

Files and links (1)

url

https://doi.org/10.1097/INF.0b013e3181cfb65fView

Published (Version of record) Open Access

Abstract

We describe hospitalization trends of invasive pneumococcal disease (IPD) among human immunodeficiency virus-infected individuals <25 years of age since the introduction of highly active antiretroviral therapy (HAART) and the 7-valent pneumococcal conjugate vaccine (PCV7) in the United States, using the Nationwide Inpatient Sample. We estimated national trends of IPD hospitalizations during 3 periods: 1994 to 1995 (pre-HAART and pre-PCV7 era); 1998 to 1999 (HAART and pre-PCV7 era); and 2004 to 2005 (HAART and early PCV7 era). The number of IPD hospitalizations among human immunodeficiency virus-infected children and youth <25 years in the United States declined by 78.7% between 1994/1995 and 2004/2005 (P = 0.03). This decrease was more pronounced among younger children.

Adolescent

Antiretroviral Therapy, Highly Active

Child

Child, Preschool

Female

Heptavalent Pneumococcal Conjugate Vaccine

HIV Infections - drug therapy

HIV Infections - epidemiology

HIV Infections - microbiology

HIV-1

Hospitalization - statistics & numerical data

Humans

Infant

Male

Odds Ratio

Pneumococcal Infections - epidemiology

Pneumococcal Infections - virology

Pneumococcal Vaccines - administration & dosage

United States - epidemiology

Young Adult

Details

Title: Subtitle: Hospitalizations for invasive pneumococcal disease among human immunodeficiency virus-1 infected children, adolescents and young adults in the United States in the era of highly active antiretroviral therapy and the conjugate pneumococcal vaccine
Creators: Athena P Kourtis - National Center for Chronic Disease Prevention and Health Promotion
Sascha Ellington
Pooja Bansil
Denise J Jamieson
Samuel F Posner
Resource Type: Journal article
Publication Details: The Pediatric infectious disease journal, Vol.29(6), pp.561-563
DOI: 10.1097/INF.0b013e3181cfb65f
PMID: 20094005
ISSN: 0891-3668
eISSN: 1532-0987
Language: English
Date published: 06/2010
Academic Unit: Obstetrics and Gynecology; VPMA - Administration
Record Identifier: 9984446404202771

Metrics

9 Record Views

3 Times Cited - Web of Science