Journal article
Host range restriction of vesicular stomatitis virus on duck embryo cells
Virology (New York, N.Y.), Vol.85(2), pp.612-616
1978
DOI: 10.1016/0042-6822(78)90466-X
PMID: 208241
Abstract
Vesicular stomatitis virus (VSV) plaque formation and replication are restricted in duck embryo cells compared to chick embryo cells. Mutants of VSV which replicate normally on both chick and duck cells were isolated. The duck-adapted mutant, when passed through chick cells, retains its ability to grow normally on duck cells. This indicates that the ability of this virus to grow on duck cells is due to mutation rather than to host-controlled modification. VSV is restricted in duck cells but not in quail or pheasant embryo cells which follows the evolutionary relationship of these species. Newcastle disease virus and Rous sarcoma virus are restricted in duck cells also. Virus-specific protein synthesis of the wild-type VSV is greatly reduced in duck cells compared to chick cells. A structural protein of the duck cell-adapted mutant is altered.
Details
- Title: Subtitle
- Host range restriction of vesicular stomatitis virus on duck embryo cells
- Creators
- Warren Levinson - University of California, San FranciscoHermann Oppermann - University of California, San FranciscoPeter Rubenstein - University of California, San FranciscoJean Jackson - University of California, San Francisco
- Resource Type
- Journal article
- Publication Details
- Virology (New York, N.Y.), Vol.85(2), pp.612-616
- DOI
- 10.1016/0042-6822(78)90466-X
- PMID
- 208241
- NLM abbreviation
- Virology
- ISSN
- 0042-6822
- eISSN
- 1096-0341
- Publisher
- Elsevier Inc
- Language
- English
- Date published
- 1978
- Academic Unit
- Stead Family Department of Pediatrics; Biochemistry and Molecular Biology; Internal Medicine
- Record Identifier
- 9984293075102771
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