Journal article
How Much Antibiotic Suspension Is Enough?
Pediatrics (Evanston), Vol.106(1), pp.e10-e10
07/01/2000
DOI: 10.1542/peds.106.1.e10
PMID: 10878142
Abstract
Objectives.
Pilot data suggest that inadequate antibiotic volumes are often dispensed. Study goals were to determine the frequency of inadequate antibiotic volumes dispensed by local pharmacies, develop prescription-writing guidelines to ensure that adequate antibiotic suspension volumes are dispensed, and document the adequacy of verbal/written counseling pharmacists provide.
Methods.
Sixty-one local pharmacies filled prescriptions for penicillin potassium (PCN; 250 mg/5 mL [5 mL orally 3 times daily for 10 days]) and Bactrim (trimethoprim-sulfamethoxazole [TMP-SMX] 5 mL orally twice daily for 10 days). The prescriptions noted only to “dispense a 10-day supply.” Volumes were measured first as total amount dispensed and then into total doses dispensed. Written/verbal instructions were documented.
Results.
The volume of PCN dispensed was 195 ± 25 mL (range: 105–222 mL) for an average of 29.4 doses, where 30 doses were needed. TMP-SMX dispensed had a volume of 107 ± 5 mL (range: 98–120 mL) resulting in an average of 16.5 doses, where 20 doses were needed. Twenty pharmacies (33%) did not dispense a measuring device. Verbal counseling by the pharmacist and written instructions were not uniformly given.
Conclusions.
We suggest calculating the actual volume needed plus an additional 10% to 30% of volume (depending on the viscosity). The prescription should also request a medication-measuring/administering device. Patient counseling and instruction should be expanded.
Details
- Title: Subtitle
- How Much Antibiotic Suspension Is Enough?
- Creators
- Lois B. Dusdieker - University of IowaJody R. Murph - University of IowaGary Milavetz - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Pediatrics (Evanston), Vol.106(1), pp.e10-e10
- DOI
- 10.1542/peds.106.1.e10
- PMID
- 10878142
- ISSN
- 0031-4005
- eISSN
- 1098-4275
- Language
- English
- Date published
- 07/01/2000
- Academic Unit
- Pharmacy; Stead Family Department of Pediatrics; Pharmacy Practice and Science
- Record Identifier
- 9984365892702771
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