How does ivabradine effect erectile dysfunction in patients with heart failure?

Fatih Aydin; Serkan Bektur; Yasin Tasdelen; Yuksel Kivrak; Ayse Huseyinoglu Aydin

doi:10.5603/KP.a2017.0095

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How does ivabradine effect erectile dysfunction in patients with heart failure?

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How does ivabradine effect erectile dysfunction in patients with heart failure?

Fatih Aydin, Serkan Bektur, Yasin Tasdelen, Yuksel Kivrak and Ayse Huseyinoglu Aydin

Kardiologia polska (1957), Vol.75(9), pp.893-898

01/01/2017

DOI: 10.5603/KP.a2017.0095

PMID: 28541595

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Abstract

Background: Erectile dysfunction (ED) is the inability or insufficiency of penile erection that causes dissatisfaction during sexual intercourse. ED is seen in patients with heart failure (HF), ranging from 56% to 81% depending on the severity. Patients usually blame their cardiovascular medications for their ED. Ivabradine is used for antianginal effects, to improve exercise intolerance, and to decrease mortality in patients with HF. Most beta-blockers are known to cause ED, but unlike beta-blockers the effect of ivabradine over ED has never been evaluated. Aim: We investigated the effect of ivabradine on ED in patients with HF. Methods: Thirty-one patients with HF (all men) under optimal treatment for HF (except ivabradine) were recruited. Patients were evaluated with the internationally validated Sexual Health Inventory for Men (SHIM) questionnaire before the initiation of ivabradine and at the sixth month of the treatment. SHIM scores previous to treatment and at six months were compared using Wilcoxon signed rank test. A p value < 0.05 was accepted as statistically significant. Results: At six months of follow-up after the initiation of ivabradine, a significant increase in patients with normal libido was found (p < 0.001). Conclusions: This is a novel study that evaluates the effect of ivabradine on human with HF. Ivabradine improved libido in patients with HF.

Cardiac & Cardiovascular Systems

Cardiovascular System & Cardiology

Life Sciences & Biomedicine

Science & Technology

Details

Title: Subtitle: How does ivabradine effect erectile dysfunction in patients with heart failure?
Creators: Fatih Aydin - Eskişehir City Hospital
Serkan Bektur - Eskişehir City Hospital
Yasin Tasdelen - Edremit State Hosp, Dept Psychiat, Edremit, Turkey
Yuksel Kivrak - Kafkas University
Ayse Huseyinoglu Aydin - Eskişehir City Hospital
Resource Type: Journal article
Publication Details: Kardiologia polska (1957), Vol.75(9), pp.893-898
DOI: 10.5603/KP.a2017.0095
PMID: 28541595
NLM abbreviation: Kardiol Pol
ISSN: 0022-9032
eISSN: 1897-4279
Publisher: Via Medica
Number of pages: 6
Language: English
Date published: 01/01/2017
Academic Unit: Internal Medicine
Record Identifier: 9984694749102771

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