Human Papillomavirus (HPV)-Related Carcinoma of the Oropharynx with Squamous Cell and Adenoid Cystic Carcinoma-Like Features: Report of a Case

Christina K Hodgson; Rodrigo Bayon; Chris S Jensen; Robert A Robinson; Anand Rajan K D

doi:10.1007/s12105-020-01233-0

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Human Papillomavirus (HPV)-Related Carcinoma of the Oropharynx with Squamous Cell and Adenoid Cystic Carcinoma-Like Features: Report of a Case

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Human Papillomavirus (HPV)-Related Carcinoma of the Oropharynx with Squamous Cell and Adenoid Cystic Carcinoma-Like Features: Report of a Case

Christina K Hodgson, Rodrigo Bayon, Chris S Jensen, Robert A Robinson and Anand Rajan K D

Head & neck pathology (Totowa, N.J.), Vol.15(3), pp.1007-1016

09/2021

DOI: 10.1007/s12105-020-01233-0

PMCID: PMC8384984

PMID: 33048304

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8384984View

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Abstract

We describe the heretofore unreported case of an HPV-related carcinoma of the palatine tonsil with distinct areas of squamous cell- and adenoid cystic carcinoma-like differentiation in a 54-year old patient. The morphological, immunophenotypic and molecular findings of the tumor are illustrated. We discuss the parallels between the tumor and HPV-related multiphenotypic sinonasal carcinoma (HMSC) which is well-known to exhibit adenoid cystic carcinoma-like features. A review of the literature of high-risk HPV-associated non-squamous carcinomas of the oropharynx is presented.

Carcinoma, Adenoid Cystic - pathology

Carcinoma, Adenoid Cystic - virology

Human papillomavirus 16

Humans

Male

Middle Aged

Papillomavirus Infections - complications

Squamous Cell Carcinoma of Head and Neck - pathology

Squamous Cell Carcinoma of Head and Neck - virology

Tonsillar Neoplasms - pathology

Tonsillar Neoplasms - virology

Details

Title: Subtitle: Human Papillomavirus (HPV)-Related Carcinoma of the Oropharynx with Squamous Cell and Adenoid Cystic Carcinoma-Like Features: Report of a Case
Creators: Christina K Hodgson - University of Iowa Hospitals and Clinics
Rodrigo Bayon - University of Iowa
Chris S Jensen - University of Iowa
Robert A Robinson - University of Iowa
Anand Rajan K D - Department of Pathology, University of Iowa Hospitals and Clinics, 5239D 200 Hawkins Drive, Iowa City, IA, 52242, USA. anand-rajand@uiowa.edu
Resource Type: Journal article
Publication Details: Head & neck pathology (Totowa, N.J.), Vol.15(3), pp.1007-1016
DOI: 10.1007/s12105-020-01233-0
PMID: 33048304
PMCID: PMC8384984
ISSN: 1936-055X
eISSN: 1936-0568
Language: English
Date published: 09/2021
Academic Unit: Oral Pathology, Radiology and Medicine; Pathology; Otolaryngology
Record Identifier: 9984311442902771

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