Human macrophage response to L. (Viannia) panamensis: microarray evidence for an early inflammatory response

Carolina Ramírez; Yira Díaz-Toro; Jair Tellez; Tiago M Castilho; Ricardo Rojas; Nicholas A Ettinger; Irina Tikhonova; Neal D Alexander; Liliana Valderrama; Janet Hager; Mary E Wilson; Aiping Lin; Hongyu Zhao; Nancy G Saravia; Diane McMahon-Pratt

doi:10.1371/journal.pntd.0001866

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Human macrophage response to L. (Viannia) panamensis: microarray evidence for an early inflammatory response

Journal article

Open access

Peer reviewed

Human macrophage response to L. (Viannia) panamensis: microarray evidence for an early inflammatory response

Carolina Ramírez, Yira Díaz-Toro, Jair Tellez, Tiago M Castilho, Ricardo Rojas, Nicholas A Ettinger, Irina Tikhonova, Neal D Alexander, Liliana Valderrama, Janet Hager, …

PLoS neglected tropical diseases, Vol.6(10), pp.e1866-e1866

2012

DOI: 10.1371/journal.pntd.0001866

PMCID: PMC3493378

PMID: 23145196

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Abstract

Previous findings indicate that susceptibility to Leishmania (Viannia) panamensis infection of monocyte-derived macrophages from patients and asymptomatically infected individuals were associated with the adaptive immune response and clinical outcome.

Host-Pathogen Interactions

Macrophages - parasitology

Leishmania guyanensis - immunology

RNA, Messenger - biosynthesis

Time Factors

Microarray Analysis

Humans

RNA, Messenger - genetics

Gene Expression Profiling

Macrophages - immunology

Details

Title: Subtitle: Human macrophage response to L. (Viannia) panamensis: microarray evidence for an early inflammatory response
Creators: Carolina Ramírez - Centro Internacional de Entrenamiento e Investigaciones Médicas (CIDEIM), Cali, Colombia
Yira Díaz-Toro
Jair Tellez
Tiago M Castilho
Ricardo Rojas
Nicholas A Ettinger
Irina Tikhonova
Neal D Alexander
Liliana Valderrama
Janet Hager
Mary E Wilson
Aiping Lin
Hongyu Zhao
Nancy G Saravia
Diane McMahon-Pratt
Resource Type: Journal article
Publication Details: PLoS neglected tropical diseases, Vol.6(10), pp.e1866-e1866
DOI: 10.1371/journal.pntd.0001866
PMID: 23145196
PMCID: PMC3493378
NLM abbreviation: PLoS Negl Trop Dis
ISSN: 1935-2735
eISSN: 1935-2735
Publisher: United States
Grant note: U19 AI065866 / NIAID NIH HHS R01 AI093775 / NIAID NIH HHS T32 GM007337 / NIGMS NIH HHS D43 TW006589 / FIC NIH HHS AI076233 / NIAID NIH HHS TMRC P50 AI-30639 / NIAID NIH HHS AI045540 / NIAID NIH HHS 1U19 AI065866 / NIAID NIH HHS 1D43TW006589 / FIC NIH HHS
Language: English
Date published: 2012
Academic Unit: Microbiology and Immunology; International Programs; Epidemiology; Internal Medicine
Record Identifier: 9984001205302771

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