Journal article
Hydrogen peroxide and hydroxyl free radical production by hematoporphyrin derivative, ascorbate and light
Cancer letters, Vol.25(3), pp.297-304
01/1985
DOI: 10.1016/S0304-3835(15)30009-4
PMID: 2982479
Abstract
Photofrin II, a commercial preparation of a hematoporphyrin derivative containing a high proportion of the active di-hematoporphyrin ether, was found to convert oxygen to hydrogen peroxide and hydroxyl free radicals in the presence of ascorbate and light. In addition, a light-dependent increase in the ascorbate free radical concentration was observed in hematoporphyrin derivative/ascorbate solutions with subsequent oxidation of ascorbate.
Details
- Title: Subtitle
- Hydrogen peroxide and hydroxyl free radical production by hematoporphyrin derivative, ascorbate and light
- Creators
- GARRY R BUETTNERMICHAEL J NEED
- Resource Type
- Journal article
- Publication Details
- Cancer letters, Vol.25(3), pp.297-304
- DOI
- 10.1016/S0304-3835(15)30009-4
- PMID
- 2982479
- ISSN
- 0304-3835
- eISSN
- 1872-7980
- Language
- English
- Date published
- 01/1985
- Academic Unit
- Radiation Oncology
- Record Identifier
- 9984047879502771
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