Hypocellular Plaque-Like CD34-Positive Dermal Fibroma (Medallion-Like Dermal Dendrocyte Hamartoma) Presenting as a Skin-Colored Dermal Nodule

Krishna A J Mutgi; Pooja Chitgopeker; Heather Ciliberto; Mary S Stone

doi:10.1111/pde.12726

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Hypocellular Plaque-Like CD34-Positive Dermal Fibroma (Medallion-Like Dermal Dendrocyte Hamartoma) Presenting as a Skin-Colored Dermal Nodule

Journal article

Peer reviewed

Hypocellular Plaque-Like CD34-Positive Dermal Fibroma (Medallion-Like Dermal Dendrocyte Hamartoma) Presenting as a Skin-Colored Dermal Nodule

Krishna A J Mutgi, Pooja Chitgopeker, Heather Ciliberto and Mary S Stone

Pediatric dermatology, Vol.33(1), pp.e16-e19

01/2016

DOI: 10.1111/pde.12726

PMID: 26645569

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Abstract

Plaque-like CD34-positive dermal fibromas, also known as medallion-like dermal dendrocyte hamartomas (MDDHs), are a recently recognized group of congenital and acquired spindle cell neoplasms that may appear histologically similar to dermatofibrosarcoma protuberans. Recognizing the clinical heterogeneity of this neoplasm and the subtle pathologic differences are crucial to making the correct diagnosis and avoiding the aggressive surgical intervention required to treat a dermatofibrosarcoma protuberans. We present the case of a 9-year-old girl with an acquired variant of a plaque-like CD34-positive dermal fibroma without clinical epidermal change. Our case expands the clinical spectrum to include an acquired variant of a plaque-like CD34-positive dermal fibroma without clinical epidermal change. Examination of more cases is needed to determine whether all clinical variants are truly subtypes of the same neoplasm or represent distinct CD34-positive spindle cell proliferations.

Skin Neoplasms - pathology

Diagnosis, Differential

Antigens, CD34 - metabolism

Fibroma - metabolism

Humans

Female

Child

Fibroma - pathology

Skin Neoplasms - metabolism

Details

Title: Subtitle: Hypocellular Plaque-Like CD34-Positive Dermal Fibroma (Medallion-Like Dermal Dendrocyte Hamartoma) Presenting as a Skin-Colored Dermal Nodule
Creators: Krishna A J Mutgi - Department of Dermatology, University of Iowa Hospitals and Clinics, Iowa City, Iowa
Pooja Chitgopeker - Department of Dermatology, University of Iowa Hospitals and Clinics, Iowa City, Iowa
Heather Ciliberto - Department of Dermatology, University of Iowa Hospitals and Clinics, Iowa City, Iowa
Mary S Stone - Department of Dermatology, University of Iowa Hospitals and Clinics, Iowa City, Iowa
Resource Type: Journal article
Publication Details: Pediatric dermatology, Vol.33(1), pp.e16-e19
Publisher: United States
DOI: 10.1111/pde.12726
PMID: 26645569
ISSN: 0736-8046
eISSN: 1525-1470
Language: English
Date published: 01/2016
Academic Unit: Dermatology; Pathology
Record Identifier: 9984025451002771

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