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Identification and treatment of metabolic complications in pediatric obesity
Journal article   Peer reviewed

Identification and treatment of metabolic complications in pediatric obesity

Katie Larson Ode, Brigitte I Frohnert and Brandon M Nathan
Reviews in endocrine & metabolic disorders, Vol.10(3), pp.167-188
09/2009
DOI: 10.1007/s11154-009-9115-7
PMCID: PMC5504917
PMID: 19809879
url
http://doi.org/10.1007/s11154-009-9115-7View
Open Access

Abstract

Metabolic consequences of obesity including insulin resistance, type 2 diabetes mellitus, hyperlipidemia, hypertension, polycystic ovarian syndrome, and nonalcoholic fatty liver infiltration are rapidly emerging in the pediatric population. Identifying effective strategies for identifying and treating these obesity related co-morbidities in children are crucial to the prevention of future cardiovascular disease and poor health outcomes. This review discusses the pathophysiologic connections between obesity, metabolic disease and cardiovascular risk. Current evidence and recommendations for screening and treatment for the metabolic consequences of pediatric obesity are reviewed.
Metabolic Syndrome Insulin resistance Fatty liver disease Type 2 diabetes mellitus Polycystic ovary disease

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