Journal article
Identification of Subpopulations of Rat Granulosa Cells: Sedimentation Properties and Hormonal Responsiveness
Endocrinology (Philadelphia), Vol.117(3), pp.1027-1034
01/01/1985
DOI: 10.1210/endo-117-3-1027
PMID: 2990865
Abstract
Ovarian granulosa cells from small follicles have generally been considered to comprise a homogeneous cell population; however, stratified arrangements of hormone receptors have been found in antral and mural granulosa cells of Graafian follicles. Using cultured granulosa cells derived from immature, hypophysectomized, estrogen-treated rats, the authors have previously shown that vasoactive intestinal peptide (VIP) as well as FSH stimulates steroid production by these cells. Dose-response analysis indicated that the actions of these hormones were additive, suggesting the presence of subpopulations of granulosa cells. The findings provide the basis for further morphological and biochemical analysis of subpopulations of granulosa cells during follicular development.
Details
- Title: Subtitle
- Identification of Subpopulations of Rat Granulosa Cells: Sedimentation Properties and Hormonal Responsiveness
- Creators
- Barry G Kasson - Neuroscience and PharmacologyRina Meidan - University of California, San DiegoJ. Benjamin DavorenAaron J. W Hsueh
- Resource Type
- Journal article
- Publication Details
- Endocrinology (Philadelphia), Vol.117(3), pp.1027-1034
- DOI
- 10.1210/endo-117-3-1027
- PMID
- 2990865
- ISSN
- 0013-7227
- eISSN
- 1945-7170
- Language
- English
- Date published
- 01/01/1985
- Academic Unit
- Neuroscience and Pharmacology
- Record Identifier
- 9984303854202771
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