Journal article
Identifying consensus and areas for future research in chondrosarcoma : a report from the Birmingham Orthopaedic Oncology Meeting
The bone & joint journal, Vol.107-B(2), pp.246-252
02/01/2025
DOI: 10.1302/0301-620X.107B2.BJJ-2024-0643.R1
PMID: 39889743
Abstract
The Birmingham Orthopaedic Oncology Meeting (BOOM), held in January 2024, convened 309 delegates from 53 countries to discuss and refine 21 consensus statements on the optimal management of chondrosarcoma.AimsThe Birmingham Orthopaedic Oncology Meeting (BOOM), held in January 2024, convened 309 delegates from 53 countries to discuss and refine 21 consensus statements on the optimal management of chondrosarcoma.With representation from Europe (43%; n = 133), North America (17%; n = 53), South America (16%; n = 49), Asia (13%; n = 40), Australasia (5%; n = 16), the Middle East (4%; n = 12), and Africa (2%; n = 6), the combined experience of treating bone sarcomas among attendees totalled approximately 30,000 cases annually, equivalent to 66 years of experience in the UK alone. The meeting's process began with the formation of a local organizing committee, regional leads, and a scientific committee comprising representatives from 150 specialist units across 47 countries. Supported by major orthopaedic oncology organizations, the meeting used a modified Delphi process to develop consensus statements through online questionnaires, thematic groupings, narrative reviews, and anonymous pre-meeting polling.MethodsWith representation from Europe (43%; n = 133), North America (17%; n = 53), South America (16%; n = 49), Asia (13%; n = 40), Australasia (5%; n = 16), the Middle East (4%; n = 12), and Africa (2%; n = 6), the combined experience of treating bone sarcomas among attendees totalled approximately 30,000 cases annually, equivalent to 66 years of experience in the UK alone. The meeting's process began with the formation of a local organizing committee, regional leads, and a scientific committee comprising representatives from 150 specialist units across 47 countries. Supported by major orthopaedic oncology organizations, the meeting used a modified Delphi process to develop consensus statements through online questionnaires, thematic groupings, narrative reviews, and anonymous pre-meeting polling.Strong (> 80%) consensus was achieved on 19 out of 21 statements, reflecting agreement among delegates. Key areas of consensus included the role of radiology in diagnosis and surveillance, the management of locally recurrent disease, and the treatment of dedifferentiated chondrosarcoma. Notably, there was agreement that routine chemotherapy has no role in chondrosarcoma treatment, and radiological surveillance is safe for intraosseous chondrosarcomas. Despite the overall consensus, areas of controversy remain, particularly regarding the treatment of atypical cartilage tumours and surgical margins. These unresolved issues underscore the need for further research and collaboration within the orthopaedic oncology community.ResultsStrong (> 80%) consensus was achieved on 19 out of 21 statements, reflecting agreement among delegates. Key areas of consensus included the role of radiology in diagnosis and surveillance, the management of locally recurrent disease, and the treatment of dedifferentiated chondrosarcoma. Notably, there was agreement that routine chemotherapy has no role in chondrosarcoma treatment, and radiological surveillance is safe for intraosseous chondrosarcomas. Despite the overall consensus, areas of controversy remain, particularly regarding the treatment of atypical cartilage tumours and surgical margins. These unresolved issues underscore the need for further research and collaboration within the orthopaedic oncology community.BOOM represents the largest global consensus meeting in orthopaedic oncology, providing valuable guidance for clinicians managing chondrosarcoma worldwide. The consensus statements offer a reference for clinical practice, highlight key research priorities, and aim to improve patient outcomes on a global scale.ConclusionBOOM represents the largest global consensus meeting in orthopaedic oncology, providing valuable guidance for clinicians managing chondrosarcoma worldwide. The consensus statements offer a reference for clinical practice, highlight key research priorities, and aim to improve patient outcomes on a global scale.
Details
- Title: Subtitle
- Identifying consensus and areas for future research in chondrosarcoma : a report from the Birmingham Orthopaedic Oncology Meeting
- Creators
- Lee M Jeys - Royal Orthopaedic HospitalBenjamin MillerGuy V Morris - Royal Orthopaedic HospitalVineet J Kurisunkal - Royal Orthopaedic HospitalEduardo Botello - Pontificia Universidad Católica de ChileRichard A Boyle - Royal Prince Alfred HospitalWalid Ebeid - Cairo UniversityMatthew T Houdek - Mayo ClinicAjay Puri - Homi Bhabha National InstitutePietro Ruggieri - University of PaduaBernadette Brennan - University of UlsterMinna K Laitinen - Helsinki University HospitalSantiago Abad RepisoHesham AbdelbaryAlejandro Abiad MejiaAhmed A AboodJuan C Abril MartinAdesegun AbuduKeisuke AeAyman Abu ElhamdMarthelena AcostaManish AgarwalVivek Ajit SinghToru AkiyamaIbrahim AlshaygyJose I AlbergoJohn AlexanderPatricio A AlfaroBugra AlpanJose Amaya-ValeroMegan AndersonDimosthenis AndreouLucas AnnabellChristopher AnthonyAhmed AoudeIraia Arteagoitia-ColinoApichat AsavamongkolkulWilliam AstonLibe Asua MentxakaChristine AzzopardiThomas Baad-HansenIsmail T BadrFrancisco Baixauli-GarciaGavin BakerTessa BalachGiacomo G BaldiJanie BarryGeorges BasileStefano BastoniMohammad BasukiHenrik BauerLee BaylissRicardo G BeckerAngad BediJoseph BeneveniaFrancisco BengoaPeter BerghMarko BergovecNicholas BernthalOdion BinitieDavid BoddieMichele BoffanoPatricia Bonilla HuertasAnna B BorgognoniRajesh BotchuJos BramerRahat BrarHarriet Branford-WhiteDemien BroekhuisSamuel E BroidaTymoteusz BudnyZachary D BurkeJorge CabrolierJose A Calvo-HaroJorge R Calvo TapiesRodrigo CardosoRichard Carey SmithPedro I CarvalloNicolas Casales FresengaJose M CasanovaOscar CeballosJuan L Cebrian ParraSara Chacon CartayaChung M ChanYoon J ChoPeter ChoongYang-Guk ChungDawid CiechanowiczMiguel A Clara-AltamiranoDavid CleverSebastian M ColinaLuis ConsuegraCory CouchGillian CribbCarlos CuervoLaurence A CusickSolomon DadiaTanios DagherDietmar DammererMark DaviesNerys DaviesLuis P de la Rosa MartinoFrancisco J de Santos de la FuenteMarieke Fuente de VaalClaudia DeckersJavier Delgado ObandoShaneel DeoNiklas DeventerClaudia Di BellaGregory DomsonDavide M DonatiDesiree M DorleijnJacques Du ToitDebra DunneRodolfo Duran CiarrochiElina EkmanAhmed M El GhoneimyMakoto EndoLevent EralpMahmoud EtaiwiScott EvansRobin EvrardWill EwardAlberto FaresePeter C FergusonPedro F Ferreira CardosoFabrice FiorenzaMichael FlintHector FloresJoao FreitasBruno FuchsTomohiro FujiwaraPhilipp T FunovicsMarcos Galli SerraZakareya GamieCarlos Garces-ZarzalejoAaron GazendamCarsten GebertJasper G GerbersCraig GerrandGhaith Abou-NouarMichelle GhertKanishka M GhoshMax GibbonsLuis C Gomez-MierJesus Gomez-VallejoAnne Gomez-MascardMarcos R GonzalezFausto Gonzalez-LizanGeorg GoshegerStuart GoudieKrista GouldingStavros D GoumenosAnthony GriffinAshish GuliaSanjay GuptaAmit GuptaMaurice GuzmanMohammed HaithamJendrik HardesFrancisco HardoyYusuf HasanGeorg HauerHelard HavardRex HaydonJohn HealeyNerea Hernandez GonzalezAdriana Hernandez-LopezAsle HeslaMatthew HessThomas HiltonChindanai HongsaprabhasFrancis HornicekKeith HoskingEleanor HoughtonOluwaseyi K IdowuJoseph IppolitoMarc IslerShintaro IwataJake JagielloNeil JenkinsThomas JenkinsCharlotte JeysTom JeysLuke JohnsonAndy JohnstonMin W JooPaul C JutteKadri KaldasAmar KamatSudhir KannanBilal KapanciZeeshan KhanHiroshi KobayashiYehuda KollenderSebastian KoobDaniel KotrychRichard KyteJose M Lamo de EspinosaAlexander L LazaridesLouis-Romee Le NailPawel LegoszBurkhard LehnerAndreas LeithnerMaryse LejolyValerae O LewisPeng LinFrancisco LinaresSantiago A Lozano-CalderonAshish MahendraFerdiansyah MahyudinFermin J Mandia ManceboSara M TorrejonChristian MarxEric MascardJean-Camille MatteiLouise McCulloughSam McMahonManuel R Medellin RinconShinji MiwaGustavo Molina UribeBryan MoonRhidian Morgan-JonesDiego J Moriel GarcescoCarol MorrisSteward MorrisonSophie MottardMarcio MouraLinde MusterRobert NakayamaPrashant NarhariAna NavasPrakash NayakJohannes NeugebauerErik T NewmanJyrki NieminenEmmy NyqvistLukas NystromSarah O'Reilly-HarbidgeGary O'TooleVania OliveiraAndré OlivierMohamed OmarEduardo J Ortiz-CruzHarzem OzgerKorhan OzkanElisa PalaEmanuela PalmeriniGrant PangPanayiotis PapagelopoulosGiovanni ParaliticciMichael C ParrySam PattonDavid PeakeAna Peiro IbanezIsrael Perez MunozGanapathy R PerianayagamMichael M PetersenJoris PloegmakersRobin PollockGerard PowellJuan PretellJan PuetzlerFaisal QamarAnand RajaRaja B RajasekaranDipak RamkumarR L RandallKenneth S RankinKevin A RaskinKumaran RassppanLauris RepsaMickael RoparsPeter RoseWael SadekGerman SalcedoAasim SaleemiAndrea SambriHartej SarRoberto ScanferlaThomas SchubertJan SchwarzeGuido ScocciantiAshley ScrimshireTetsuya SekitaAhmad ShehadehAhmed ShoaibBhim ShreemalFelix ShumelinskyGeoffrey SiegelClaudio SilveriRobert SilverwoodFriedl SinnaeveJerome SisonAndrea SladeMaria A SmolleFranz SnymanScott SommervilleSahil SoodAndre SpiguelHugo St-YvesEric L StaalsSilvia StacchiottiNikolas StavropoulosPeter SteadmanJonathan D StevensonMikaela SullivanGwen SysBartlomiej SzostakowskiAngela TamburiniYuta TaniguchiThomas TempleChristoph TheilJoachim ThorkildsenMeagan TibboRoger TillmanYu TodaKaspar TootsiFerran Torner RubiesFrank TraubIoannis TrikoupisPanagiotis TsagkozisKim TsoiHiroyuki TsuchiyaVeli-Matti VainioAntonio ValcarcelJuan ValenciaAnnelies Van BeeckMichel Van de SandeThomas Van Den BergheIngrid Van de GeestLizz Van der HeijdenRobert Van der WalKirsten Van LangeveldeGualter VazRoberto Velez VillaFloortje VerspoorKoenraad VerstraeteJulia VisgaussOleg VyrvaHazem WafaSebastian WalterWan F Wan IsmailEdward WangPatrick Q WangDavid WarnockJoel WerierWolfram WeschenfelderKwok-Chuen WongMarjan Woulthuyzen-BakkerJay WunderIndica WysingheNorio YamamotoZhaoming YeSeung-Jae YoonSuraya Zainul AbidinTomas ZamoraPierluca ZecchettoLiuzhe ZhangJuan P ZumarragaDomenico A Campanacci
- Resource Type
- Journal article
- Publication Details
- The bone & joint journal, Vol.107-B(2), pp.246-252
- Publisher
- BRITISH EDITORIAL SOC BONE & JOINT SURGERY; LONDON
- DOI
- 10.1302/0301-620X.107B2.BJJ-2024-0643.R1
- PMID
- 39889743
- ISSN
- 2049-4408
- eISSN
- 2049-4408
- Grant note
- state for university-level research, Helsinki University Hospital, Finland: TYH 2023317
The open-access publication of this work was supported by funding from the state for university-level research, Helsinki University Hospital, Finland, under grant number TYH 2023317.
- Language
- English
- Date published
- 02/01/2025
- Academic Unit
- Orthopedics and Rehabilitation
- Record Identifier
- 9984781374402771
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