Image-Based Biomarkers in Clinical Practice

John E Bayouth; Thomas L Casavant; Michael M Graham; Milan Sonka; Manickam Muruganandham; John M Buatti

doi:10.1016/j.semradonc.2010.11.003

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Image-Based Biomarkers in Clinical Practice

Journal article

Open access

Peer reviewed

Image-Based Biomarkers in Clinical Practice

John E Bayouth, Thomas L Casavant, Michael M Graham, Milan Sonka, Manickam Muruganandham and John M Buatti

Seminars in radiation oncology, Vol.21(2), pp.157-166

2011

DOI: 10.1016/j.semradonc.2010.11.003

PMCID: PMC4270476

PMID: 21356483

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https://www.ncbi.nlm.nih.gov/pmc/articles/4270476View

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Abstract

The growth of functional and metabolically informative imaging is eclipsing anatomic imaging alone in clinical practice. The recognition that magnetic resonance (MR) and positron emission tomography (PET)-based treatment planning and response assessment are essential components of clinical practice and furthermore offer the potential of quantitative analysis being important. Extracting the greatest benefit from these imaging techniques will require refining the best combinations of multimodality imaging through well-designed clinical trials that use robust image-analysis tools and require substantial computer based infrastructure. Through these changes and enhancements, image-based biomarkers will enhance clinical decision making and accelerate the progress that is made through clinical trial research.

Details

Title: Subtitle: Image-Based Biomarkers in Clinical Practice
Creators: John E Bayouth - Department of Radiation Oncology, University of Iowa, Iowa City, IA
Thomas L Casavant - Biomedical Engineering, University of Iowa, Iowa City, IA
Michael M Graham - Radiology, University of Iowa, Iowa City, IA
Milan Sonka - Electrical Engineering, University of Iowa, Iowa City, IA
Manickam Muruganandham - Department of Radiation Oncology, University of Iowa, Iowa City, IA
John M Buatti - Department of Radiation Oncology, University of Iowa, Iowa City, IA
Resource Type: Journal article
Publication Details: Seminars in radiation oncology, Vol.21(2), pp.157-166
DOI: 10.1016/j.semradonc.2010.11.003
PMID: 21356483
PMCID: PMC4270476
NLM abbreviation: Semin Radiat Oncol
ISSN: 1053-4296
eISSN: 1532-9461
Publisher: Elsevier Inc
Grant note: 1U01 CA140206-01 / NIH
Language: English
Date published: 2011
Academic Unit: Roy J. Carver Department of Biomedical Engineering; Radiology; Electrical and Computer Engineering; Radiation Oncology; Injury Prevention Research Center; Neurosurgery; Otolaryngology; Ophthalmology and Visual Sciences
Record Identifier: 9984040393802771

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