Image-Based Treatment Planning of the Post-Lumpectomy Breast Utilizing CT and 3TMRI

Geraldine Jacobson; Gideon Zamba; Vicki Betts; M Muruganandham; Joni Buechler-Price

doi:10.4061/2011/246265

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Image-Based Treatment Planning of the Post-Lumpectomy Breast Utilizing CT and 3TMRI

Journal article

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Image-Based Treatment Planning of the Post-Lumpectomy Breast Utilizing CT and 3TMRI

Geraldine Jacobson, Gideon Zamba, Vicki Betts, M Muruganandham and Joni Buechler-Price

International journal of breast cancer, Vol.2011, pp.1-5

2011

DOI: 10.4061/2011/246265

PMCID: PMC3262557

PMID: 22295215

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Abstract

Accurate lumpectomy cavity definition is critical in breast treatment planning. We compared contouring lumpectomy cavity volume and cavity visualization score (CVS) with CT versus 3T MRI. 29 patients were imaged with CT and 3T MRI. Seven additional boost planning sets were obtained for 36 image sets total. Three observers contoured the lumpectomy cavity on all images, assigning a cavity visualization score (CVS ) of 1 to 5. Measures of consistency and agreement for CT volumes were 98.84% and 98.62%, for T1 MRI were 95.65% and 95.55%, and for T2 MRI were 97.63% and 97.71%. The mean CT, T1 MRI, and T2 MRI CVS scores were 3.28, 3.38, and 4.32, respectively. There was a highly significant difference between CT and T2 scores () and between T1 and T2 scores (). Interobserver consistency and agreement regarding volumes were high for all three modalities with T2 MRI CVS the highest. MRI may contribute to target definition in selected patients.

Details

Title: Subtitle: Image-Based Treatment Planning of the Post-Lumpectomy Breast Utilizing CT and 3TMRI
Creators: Geraldine Jacobson - Department of Radiation Oncology, University of Iowa Hospital and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA
Gideon Zamba - Department of Biostatistics, College of Public Health, The University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA
Vicki Betts - Department of Radiation Oncology, University of Iowa Hospital and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA
M Muruganandham - Department of Radiation Oncology, University of Iowa Hospital and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA
Joni Buechler-Price - Department of Radiation Oncology, University of Iowa Hospital and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA
Resource Type: Journal article
Publication Details: International journal of breast cancer, Vol.2011, pp.1-5
DOI: 10.4061/2011/246265
PMID: 22295215
PMCID: PMC3262557
NLM abbreviation: Int J Breast Cancer
ISSN: 2090-3189
eISSN: 2090-3189
Language: English
Date published: 2011
Academic Unit: Radiology; Biostatistics
Record Identifier: 9983997454102771

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