Journal article
Image-Guided Stereotactic Radiosurgery Using a Specially Designed High-Dose-Rate Linac
Medical dosimetry : official journal of the American Association of Medical Dosimetrists, Vol.32(2), pp.134-141
2007
DOI: 10.1016/j.meddos.2007.01.010
PMID: 17472892
Abstract
Stereotactic radiosurgery and image-guided radiotherapy (IGRT) place enhanced demands on treatment delivery machines. In this study, we describe a high-dose-rate output accelerator as a part of our stereotactic IGRT delivery system. The linac is a Siemens Oncor without a flattening filter, and enables dose rates to reach 1000 monitor units (MUs) per minute. Even at this high-dose-rate, the linac dosimetry system remains robust; constancy, linearity, and beam energy remain within 1% for 3 to 1000 MU. Dose profiles for larger field sizes are not flat, but they are radially symmetric and, as such, able to be modeled by a treatment planning system. Target localization is performed via optical guidance utilizing a 3-dimensional (3D) ultrasound probe coupled to an array of 4 infrared light-emitting diodes. These diodes are identified by a fixed infrared camera system that determines diode position and, by extension, all objects imaged in the room coordinate system. This system provides sub-millimeter localization accuracy for cranial applications and better than 1.5 mm for extracranial applications. Because stereotactic IGRT can require significantly longer times for treatment delivery, the advantages of the high-dose-rate design and its direct impact on IGRT are discussed.
Details
- Title: Subtitle
- Image-Guided Stereotactic Radiosurgery Using a Specially Designed High-Dose-Rate Linac
- Creators
- John E Bayouth - Department of Radiation Oncology, Holden Comprehensive Cancer Center, University of Iowa Hospitals and Clinics, Iowa City, IAHeather S Kaiser - Department of Radiation Oncology, Holden Comprehensive Cancer Center, University of Iowa Hospitals and Clinics, Iowa City, IAMark C Smith - Department of Radiation Oncology, Holden Comprehensive Cancer Center, University of Iowa Hospitals and Clinics, Iowa City, IAEdward C Pennington - Department of Radiation Oncology, Holden Comprehensive Cancer Center, University of Iowa Hospitals and Clinics, Iowa City, IAKathleen M Anderson - Department of Radiation Oncology, Holden Comprehensive Cancer Center, University of Iowa Hospitals and Clinics, Iowa City, IATimothy C Ryken - Department of Neurosurgery, Holden Comprehensive Cancer Center, University of Iowa Hospitals and Clinics, Iowa City, IAJohn M Buatti - Department of Radiation Oncology, Holden Comprehensive Cancer Center, University of Iowa Hospitals and Clinics, Iowa City, IA
- Resource Type
- Journal article
- Publication Details
- Medical dosimetry : official journal of the American Association of Medical Dosimetrists, Vol.32(2), pp.134-141
- Publisher
- Elsevier Inc
- DOI
- 10.1016/j.meddos.2007.01.010
- PMID
- 17472892
- ISSN
- 0958-3947
- eISSN
- 1873-4022
- Language
- English
- Date published
- 2007
- Academic Unit
- Radiation Oncology; Neurosurgery; Otolaryngology
- Record Identifier
- 9984040490802771
Metrics
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