Imaging evaluation and management of liver infections: a multimodality review

Benjamin Srivastava; Yashant Aswani; Cristina O. Menias; Rachita Khot; Nadia Solomon; Victoria Chernyak

doi:10.1007/s00261-026-05379-3

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Imaging evaluation and management of liver infections: a multimodality review

Journal article

Peer reviewed

Imaging evaluation and management of liver infections: a multimodality review

Benjamin Srivastava, Yashant Aswani, Cristina O. Menias, Rachita Khot, Nadia Solomon and Victoria Chernyak

Abdominal radiology (New York)

02/11/2026

DOI: 10.1007/s00261-026-05379-3

PMID: 41670675

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Abstract

Liver infections comprise a large category of hepatic diseases which vary in etiology and geographic distribution. They remain a significant cause of morbidity and mortality globally and require prompt diagnosis and management. Because clinical and laboratory findings may not be definitive, imaging often plays an important role in the diagnosis, characterization, and follow-up of hepatic infections. Advanced imaging techniques increase accuracy of diagnosis of specific infectious pathogens and in some cases provide the means of differentiation of various infections from other hepatic pathologies and conditions, most notably, neoplasms. Radiologists must be familiar with the key imaging findings and differential features in the multimodality approach to these conditions. This review provides a comprehensive overview of common and uncommon hepatic infections, highlighting key imaging features, characteristic signs, differential diagnoses, complications, and treatment considerations. Advanced techniques utilizing major cross-sectional modalities, including but not limited to contrast-enhanced ultrasound, dual energy computed tomography, and diffusion-weighted and contrast-enhanced magnetic resonance imaging will be discussed. A summary table that combines clinical, laboratory, demographic data and imaging findings will also be provided to guide diagnostic evaluation. This article aims to equip radiologists with essential tools for accurate diagnosis and timely clinical guidance.

Amebic liver abscess

Clonorchiasis and opisthorchiasis

fascioliasis

Fundal liver infection

Liver hydatid disease

Liver infections

MRI and US signs of liver abscesses and liver infections

Parasitic infection of the liver

Pyogenic liver abscess

Schistosomiasis

Syphilitic hepatitis

Tuberculous hepatitis

Viral hepatitis

Details

Title: Subtitle: Imaging evaluation and management of liver infections: a multimodality review
Creators: Benjamin Srivastava - Wilton High School, Wilton, CT, United States
Yashant Aswani - University of Iowa
Cristina O. Menias - Mayo Clinic in Arizona
Rachita Khot - Georgetown University
Nadia Solomon - Yale University
Victoria Chernyak - Columbia University
Resource Type: Journal article
Publication Details: Abdominal radiology (New York)
DOI: 10.1007/s00261-026-05379-3
PMID: 41670675
NLM abbreviation: Abdom Radiol (NY)
ISSN: 2366-004X
eISSN: 2366-0058
Publisher: Springer Nature
Language: English
Electronic publication date: 02/11/2026
Academic Unit: Radiology
Record Identifier: 9985139463202771

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