Journal article
Imaging glucose-regulated insulin secretion and gene expression in single islet β-cells: Control by AMP-activated protein kinase
Cell biochemistry and biophysics, Vol.40(S3), pp.179-190
10/2004
DOI: 10.1385/CBB:40:3:179
Abstract
The mechanisms by which changes in glucose concentration regulate gene expression and insulin secretion in pancreatic islet β-cells are only partly understood. Here we describe the development of new technologies for examining these processes at the level of single living β-cells. We also present recent findings, made using these and other techniques, which implicate a role for adenosine 5′-monophosphate-activated protein kinase in glucose signaling in these cells.
Details
- Title: Subtitle
- Imaging glucose-regulated insulin secretion and gene expression in single islet β-cells: Control by AMP-activated protein kinase
- Creators
- Guy A. Rutter - University of BristolIsabelle Leclerc - University of BristolTakashi Tsuboi - University of BristolGabriela da Silva XavierFrédérique Diraison - University of BristolQingwen Qian - University of Bristol
- Resource Type
- Journal article
- Publication Details
- Cell biochemistry and biophysics, Vol.40(S3), pp.179-190
- DOI
- 10.1385/CBB:40:3:179
- ISSN
- 1085-9195
- eISSN
- 1559-0283
- Language
- English
- Date published
- 10/2004
- Academic Unit
- Anatomy and Cell Biology
- Record Identifier
- 9984420938002771
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