Journal article
Imaging mimics of chronic recurrent multifocal osteomyelitis: avoiding pitfalls in a diagnosis of exclusion
Pediatric radiology, Vol.50(1), pp.124-136
01/2020
DOI: 10.1007/s00247-019-04510-5
PMID: 31901992
Abstract
Chronic recurrent multifocal osteomyelitis (CRMO) is a pediatric autoinflammatory disorder that is characterized by multiple sterile inflammatory bone lesions with a relapsing and remitting course. CRMO belongs to the autoinflammatory family of rheumatologic disorders based on absence of significant titers of autoantibodies and autoreactive T-lymphocytes. In absence of pathognomonic clinical, radiographic or pathological features, diagnosis can be challenging. CRMO shares imaging features with other diseases. It is important for radiologists to be able to differentiate other diseases from CRMO because prognosis varies from completely benign to frankly malignant. In this article we first present the clinical and imaging features of CRMO to help readers gain an understanding of the disease process, then discuss our imaging approach to CRMO and review other disease processes that sometimes share similar imaging findings to CRMO and review differentiating features to help avoid misdiagnoses.
Details
- Title: Subtitle
- Imaging mimics of chronic recurrent multifocal osteomyelitis: avoiding pitfalls in a diagnosis of exclusion
- Creators
- Takashi Shawn Sato - Division of Pediatric Radiology, Department of Radiology, Stead Family Children's Hospital, University of Iowa, 200 Hawkins Drive, 3889 JPP, Iowa City, IA, 52242, USA. shawn-sato@uiowa.eduPankaj Watal - Division of Pediatric Radiology, Department of Radiology, Stead Family Children's Hospital, University of Iowa, 200 Hawkins Drive, 3889 JPP, Iowa City, IA, 52242, USAPolly J Ferguson - Division of Pediatric Rheumatology, Department of Pediatrics, Stead Family Children's Hospital, University of Iowa, Iowa City, IA, USA
- Resource Type
- Journal article
- Publication Details
- Pediatric radiology, Vol.50(1), pp.124-136
- Publisher
- Germany
- DOI
- 10.1007/s00247-019-04510-5
- PMID
- 31901992
- ISSN
- 0301-0449
- eISSN
- 1432-1998
- Language
- English
- Date published
- 01/2020
- Academic Unit
- Radiology; Stead Family Department of Pediatrics; Iowa Neuroscience Institute; Rheumatology, Allergy, and Immunology
- Record Identifier
- 9984070332502771
Metrics
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