Journal article
Imaging the past: Dental pathologies and cardiovascular disease in Egyptian mummified remains
The Journal of the American Dental Association (1939), Vol.157(6), pp.639-647.e1
06/2026
DOI: 10.1016/j.adaj.2025.11.013
PMID: 41618943
Abstract
Imaging advancements markedly enhance the assessment of skeletal and dental pathologies in clinical and archaeological contexts. Among the most frequently observed dental conditions in bioarcheological studies are periodontal disease and caries, both of which can provide valuable insights into systemic conditions (eg, cardiovascular disease). When identified in mummified remains, dental pathologies offer a unique perspective on the health status and disease burden of past populations and the interplay between oral and systemic health across human history.
Using a database of computed tomographic scans of Egyptian mummies, the authors investigated the prevalence and extent of dental pathologies, including periapical lucencies and teeth with caries, and the distance from the cementoenamel junction to the alveolar crest. Regression analyses were used to examine the associations between oral health variables and vascular pathology.
Advanced demineralization, indicative of destructive carious processes, and periodontal disease were highly prevalent in this mummified cohort. Furthermore, oral pathologies were determined to be correlated with the number of calcified vascular beds, although these findings were not independent of age- or sex-related effects at large.
The authors established evidence of periodontitis, teeth with caries, and impacted teeth in mummified remains, along with correlations between oral health and cardiovascular disease.
Findings from these ancient remains highlight the long-standing presence of oral disease, reinforcing that oral health problems are not only modern. For contemporary clinicians, this historical perspective underscores the value of culturally sensitive dentistry and how population behaviors contribute to distinct oral health challenges.
Details
- Title: Subtitle
- Imaging the past: Dental pathologies and cardiovascular disease in Egyptian mummified remains
- Creators
- Atlee A Witt - Vanderbilt UniversityDerek K Smith - University of IowaRandall C Thompson - Saint Luke's HospitalGregory S Thomas - Orange Coast Memorial Medical CenterM Linda Sutherland - Orange Coast Memorial Medical CenterJames D Sutherland - Orange Coast Memorial Medical CenterDavid E Michalik - MemorialCare Long Beach Medical CenterChris J Rowan - University of Nevada, RenoKatherine D Van Schaik - Vanderbilt University
- Resource Type
- Journal article
- Publication Details
- The Journal of the American Dental Association (1939), Vol.157(6), pp.639-647.e1
- DOI
- 10.1016/j.adaj.2025.11.013
- PMID
- 41618943
- NLM abbreviation
- J Am Dent Assoc
- ISSN
- 1943-4723
- eISSN
- 1943-4723
- Publisher
- Elsevier
- Grant note
- National Endowment for the Humanities: HJ-50069-12 Marie Sklodowska-Curie Actions-Seal of Excellence grant for Mummies under the Microscope Bolzano from the European Commission Provincia Autonoma di Bolzano: 14 Paleocardiology Foundation Siemens Healthineers National Bank of Egypt Saint Luke's Hospital Foundation of Kansas City American College of Cardiology, Missouri Chapter
The study was funded in part by grant HJ-50069-12 from the National Endowment for the Humanities, awarded to Saint Luke's Mid America Heart Institute; the Marie Sklodowska-Curie Actions-Seal of Excellence grant for Mummies under the Microscope Bolzano from the European Commission, awarded to Eurac Research Institute for Mummy Studies; grant Legge 14 from the Provincia Autonoma di Bolzano, awarded to Eurac Research Institute for Mummy Studies; the Paleocardiology Foundation; Siemens Healthineers; The National Bank of Egypt; Saint Luke's Hospital Foundation of Kansas City; and The American College of Cardiology, Missouri Chapter.
- Language
- English
- Electronic publication date
- 01/30/2026
- Date published
- 06/2026
- Academic Unit
- Preventive and Community Dentistry; Biostatistics; Dental Research
- Record Identifier
- 9985134749902771
Metrics
14 Record Views