Journal article
Immune-Mediated Myelopathies: A Review of Etiologies, Diagnostic Approach, and Therapeutic Management
Seminars in neurology, Vol.41(3), pp.269-279
05/24/2021
DOI: 10.1055/s-0041-1725152
PMID: 34030191
Abstract
Abstract
Myelopathy is a broad term used to describe a heterogeneous group of disorders that affects the spinal cord; the focus of this article will be a subgroup of these disorders with an autoimmune and inflammatory-based pathology. Symptoms typically develop over hours or days and then worsen over a matter of days to weeks, but sometimes can have a more insidious or subacute presentation, which can make the diagnosis more puzzling. Despite relatively low incidence rates, almost a third of affected patients are left with severely disabling symptoms. Prompt recognition of the underlying etiology is essential so that a specific targeted therapy can be implemented for optimal outcomes. The authors discuss a systematic approach to immune-mediated myelopathies, with a focus on the unique characteristics of each that may aid in diagnosis.
Details
- Title: Subtitle
- Immune-Mediated Myelopathies: A Review of Etiologies, Diagnostic Approach, and Therapeutic Management
- Creators
- Lama Abdel-Wahed - Department of Neurology, University of Iowa Carver College of MedicineTracey A Cho - Department of Neurology, University of Iowa Hospitals and Clinics, Iowa City, Iowa
- Resource Type
- Journal article
- Publication Details
- Seminars in neurology, Vol.41(3), pp.269-279
- Publisher
- Thieme Medical Publishers, Inc
- DOI
- 10.1055/s-0041-1725152
- PMID
- 34030191
- ISSN
- 0271-8235
- eISSN
- 1098-9021
- Language
- English
- Date published
- 05/24/2021
- Academic Unit
- Neurology; Iowa Neuroscience Institute
- Record Identifier
- 9984082272602771
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