Journal article
Immune phenomena in glaucoma and conformational disorders: why is the second eye not involved?
Journal of glaucoma, Vol.23(8 Suppl 1), pp.S59-S61
10/2014
DOI: 10.1097/IJG.0000000000000115
PMCID: PMC4276141
PMID: 25275909
Abstract
Data along several lines of evidence have suggested that a systemic autoimmune response may be provoked in glaucoma and could contribute to retinal ganglion cell loss. If such an autoimmune response exists, one could predict that in cases of unilateral glaucoma, autoantibodies generated would affect both eyes, leading to damage in the unaffected, contralateral eye in an intraocular pressure-independent manner. However, such an effect has not yet been reported. There are currently no data to reconcile these contrasting observations but a review of the literature suggests a possible explanation.
Details
- Title: Subtitle
- Immune phenomena in glaucoma and conformational disorders: why is the second eye not involved?
- Creators
- Markus H Kuehn - Department of Ophthalmology and Visual Sciences, The University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242
- Resource Type
- Journal article
- Publication Details
- Journal of glaucoma, Vol.23(8 Suppl 1), pp.S59-S61
- DOI
- 10.1097/IJG.0000000000000115
- PMID
- 25275909
- PMCID
- PMC4276141
- NLM abbreviation
- J Glaucoma
- ISSN
- 1536-481X
- eISSN
- 1536-481X
- Publisher
- United States
- Grant note
- R01 EY019485 / NEI NIH HHS I01 RX001163 / RRD VA
- Language
- English
- Date published
- 10/2014
- Academic Unit
- Ophthalmology and Visual Sciences
- Record Identifier
- 9983979988702771
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