Journal article
Immune responses in influenza A virus and human coronavirus infections: an ongoing battle between the virus and host
Current Opinion in Virology, Vol.28, pp.43-52
2018
DOI: 10.1016/j.coviro.2017.11.002
PMCID: PMC5835172
PMID: 29172107
Abstract
Respiratory viruses, especially influenza A viruses and coronaviruses such as MERS-CoV, represent continuing global threats to human health. Despite significant advances, much needs to be learned. Recent studies in virology and immunology have improved our understanding of the role of the immune system in protection and in the pathogenesis of these infections and of co-evolution of viruses and their hosts. These findings, together with sophisticated molecular structure analyses, omics tools and computer-based models, have helped delineate the interaction between respiratory viruses and the host immune system, which will facilitate the development of novel treatment strategies and vaccines with enhanced efficacy.
Details
- Title: Subtitle
- Immune responses in influenza A virus and human coronavirus infections: an ongoing battle between the virus and host
- Creators
- Jian ZhengStanley Perlman
- Resource Type
- Journal article
- Publication Details
- Current Opinion in Virology, Vol.28, pp.43-52
- DOI
- 10.1016/j.coviro.2017.11.002
- PMID
- 29172107
- PMCID
- PMC5835172
- NLM abbreviation
- Curr Opin Virol
- ISSN
- 1879-6257
- eISSN
- 1879-6265
- Grant note
- DOI: 10.13039/100000002, name: NIH, award: PO1 AI060699, RO1 AI129269
- Language
- English
- Date published
- 2018
- Academic Unit
- Microbiology and Immunology; Stead Family Department of Pediatrics; Iowa Neuroscience Institute; Infectious Disease (Pediatrics)
- Record Identifier
- 9983777477102771
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