Journal article
Immunohistochemistry in Gastroenterohepatopancreatobiliary Epithelial Neoplasia: Practical Applications, Pitfalls, and Emerging Markers
Surgical pathology clinics, Vol.6(3), pp.567-609
09/2013
DOI: 10.1016/j.path.2013.06.003
PMID: 26839101
Abstract
Immunohistochemistry (IHC) has broad applications in neoplastic gastrointestinal surgical pathology. Although classically used as a diagnostic tool, IHC increasingly provides prognostic and predictive information. This review highlights 11 key uses of IHC (Box 1). Emphasis is placed on specific clinical applications and qualitative aspects of interpretation. Common pitfalls are specifically highlighted. The potential application of emerging markers is discussed in relation to several of the 11 topics. In many instances, an immunostain serves as a surrogate for specific molecular genetic events. Survey of relevant articles forms the evidence basis for this review.
Details
- Title: Subtitle
- Immunohistochemistry in Gastroenterohepatopancreatobiliary Epithelial Neoplasia: Practical Applications, Pitfalls, and Emerging Markers
- Creators
- Andrew M Bellizzi - University of Iowa Hospitals and Clinics
- Resource Type
- Journal article
- Publication Details
- Surgical pathology clinics, Vol.6(3), pp.567-609
- DOI
- 10.1016/j.path.2013.06.003
- PMID
- 26839101
- ISSN
- 1875-9181
- eISSN
- 1875-9157
- Language
- English
- Date published
- 09/2013
- Academic Unit
- Pathology
- Record Identifier
- 9984183995702771
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