Journal article
Immunologic Mechanisms of Multiple Sclerosis
Neuroimaging clinics of North America, Vol.18(4), pp.577-588
2008
DOI: 10.1016/j.nic.2008.06.009
PMID: 19068403
Abstract
Multiple sclerosis is widely recognized as the most commonly identified cause of progressive neurologic disability in young adults throughout the developed world. The disorder is clinically suspected when patients experience either acute attacks of neurologic compromise or instead are afflicted by a steadily progressive deterioration in functional capabilities. The pathophysiology of acute exacerbations is thought to be related to the development of inflammation and its consequences, within strategic and often discrete central nervous system tract systems. Although a myriad of hypotheses have been formulated to explain the underpinnings of the mechanisms that contribute to both the predilection and triggering of the multiphasic inflammatory events that personify multiple sclerosis, much remains to be done to understand fully the specific set and sequence of events that produce the disease and its cardinal features.
Details
- Title: Subtitle
- Immunologic Mechanisms of Multiple Sclerosis
- Creators
- Elliot M Frohman - Department of Neurology, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75235, USATodd Eagar - Department of Neurology, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75235, USANancy Monson - Department of Neurology, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75235, USAOlaf Stuve - Department of Neurology, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75235, USANitin Karandikar - Department of Neurology, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75235, USA
- Resource Type
- Journal article
- Publication Details
- Neuroimaging clinics of North America, Vol.18(4), pp.577-588
- Publisher
- Elsevier Inc
- DOI
- 10.1016/j.nic.2008.06.009
- PMID
- 19068403
- ISSN
- 1052-5149
- eISSN
- 1557-9867
- Language
- English
- Date published
- 2008
- Academic Unit
- Pathology
- Record Identifier
- 9984046904802771
Metrics
13 Record Views