Journal article
Impact of Obesity in Hospitalized Patients Undergoing Catheter Ablation for Atrial Fibrillation
Pacing and clinical electrophysiology, Vol.48(9), pp.1047-1058
09/2025
DOI: 10.1111/pace.70026
PMID: 40778491
Abstract
Morbid obesity is a well-known risk factor for the development of Atrial Fibrillation (AF); however, its influence in patients undergoing Catheter Ablation (CA) for AF is poorly recognized.
The NRD (2016-2020) was used to identify CA for AF. Cohorts were stratified as non-obese (BMI <25), obese (BMI 30-39), and morbidly obese (BMI ≥ 40). Multivariate regression and propensity-matched models were used.
Among 83,767 CAs for AF, 10,590 (12.6%) were morbidly obese population. On propensity-matched cohorts (N: 5741), morbid obesity was associated with higher rates of acute HF (39.1% vs. 34.5%), sudden cardiac arrest (5.6% vs. 4.7%), post-procedural bleeding (1.95% vs. 1.36%), AKI (21.7% vs. 16.3%), and respiratory complications (18.9% vs. 13.2%). Morbid obesity was also associated with higher median LOS (4 vs. 3 days) and higher total cost ($43,768 vs. $39,026). From 2016-2020, the total cost increased irrespective of the obesity status (p
< 0.05); however, LOS showed a decreasing trend for non-obese (p
< 0.05) but remained the same for morbidly obese patients (p
> 0.05). The 30-day (11.7% vs. 8.4%) and 180-day (29.9% vs. 24.9%) all-cause readmission rates were significantly higher for the morbidly obese compared to non-obese patients. Post-discharge, AF was the most common cause (69.2% & 66.8%) for 30 and 180-day readmissions. Our subgroup analysis comparing obese (BMI 30-39) to non-obese showed higher rates of periprocedural acute HF and respiratory complications (p < 0.05).
Morbid obesity in patients undergoing CA for AF was associated with higher rates of periprocedural adverse events, healthcare-related burden, and readmission rates.
Details
- Title: Subtitle
- Impact of Obesity in Hospitalized Patients Undergoing Catheter Ablation for Atrial Fibrillation
- Creators
- Shafaqat Ali - Louisiana State University Health Sciences Center ShreveportSanchit Duhan - Carle Foundation HospitalManoj Kumar - John H. Stroger, Jr. Hospital of Cook CountyBilal Hussain - Brooklyn Hospital CenterLalitsiri Atti - Sparrow Health SystemPramod Kumar Ponna - Louisiana State University Health Sciences Center ShreveportFaryal Farooq - Louisiana State University Health Sciences Center ShreveportBijeta Keisham - Weifang Medical UniversityYasar Sattar - West Virginia UniversityVijaywant Brar - Louisiana State University Health Sciences Center ShreveportZain Ul Abideen Asad - University of Oklahoma Medical CenterTarek Helmy - Louisiana State University Health Sciences Center ShreveportHakan Paydak - University of Arkansas for Medical SciencesPaari Dominic - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Pacing and clinical electrophysiology, Vol.48(9), pp.1047-1058
- DOI
- 10.1111/pace.70026
- PMID
- 40778491
- NLM abbreviation
- Pacing Clin Electrophysiol
- ISSN
- 1540-8159
- eISSN
- 1540-8159
- Publisher
- Wiley
- Language
- English
- Electronic publication date
- 08/08/2025
- Date published
- 09/2025
- Academic Unit
- Cardiovascular Medicine; Internal Medicine
- Record Identifier
- 9984944720802771
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