Journal article
Impact of Rurality on Stage IV Ovarian Cancer at Diagnosis: A Midwest Cancer Registry Cohort Study
The Journal of rural health, Vol.36(4), pp.468-475
2020
DOI: 10.1111/jrh.12419
PMCID: PMC7852624
PMID: 32077162
Abstract
Purpose
We aim to understand if rurality impacts patients’ odds of presenting with stage IV ovarian cancer at diagnosis independent of distance to primary care provider and the socioeconomic status of a patient's residential census tract.
Methods
A cohort of 1,000 women with ovarian cancer in Iowa, Kansas, and Missouri were sampled and analyzed from the cancer registries’ statewide population data. The sample contained those with a histologically confirmed primary ovarian cancer diagnosis in 2011‐2012. All variables were captured through an extension of standard registry protocol using standardized definitions and ion manuals. Chi‐square tests and a multivariable logistic regression model were used.
Findings
At diagnosis, 111 women in our sample had stage IV cancer and 889 had stage I‐III. Compared to patients with stage I‐III cancer, patients with stage IV disease had a higher average age, more comorbidities, and were more often living in rural areas. Multivariate analysis showed that rural women (vs metropolitan) had a greater odds of having stage IV ovarian cancer at diagnosis (odds ratio = 2.41 and 95% confidence interval = 1.33‐4.39).
Conclusion
Rural ovarian cancer patients have greater odds of having stage IV cancer at diagnosis in Midwestern states independent of the distance they lived from their primary care physician and the socioeconomic status of their residential census tract. Rural women's greater odds of stage IV cancer at diagnosis could affect treatment options and mortality. Further investigation is needed into reasons for these findings.
Details
- Title: Subtitle
- Impact of Rurality on Stage IV Ovarian Cancer at Diagnosis: A Midwest Cancer Registry Cohort Study
- Creators
- Kristin S Weeks - University of IowaCharles F Lynch - University of IowaMichele West - University of IowaMegan McDonald - University of Iowa Hospitals and ClinicsRyan Carnahan - University of IowaSherri L Stewart - Centers for Disease Control and PreventionOvarian Cancer Treatment StudyMary Charlton - University of Iowa
- Resource Type
- Journal article
- Publication Details
- The Journal of rural health, Vol.36(4), pp.468-475
- DOI
- 10.1111/jrh.12419
- PMID
- 32077162
- PMCID
- PMC7852624
- NLM abbreviation
- J Rural Health
- ISSN
- 0890-765X
- eISSN
- 1748-0361
- Number of pages
- 8
- Grant note
- NIH NCI Centers for Disease Control and Prevention (200‐2014‐61258) Department of Health and senior services, Missouri (U58DP006299‐01/02)
- Language
- English
- Date published
- 2020
- Academic Unit
- Epidemiology; Nursing; Obstetrics and Gynecology; Injury Prevention Research Center
- Record Identifier
- 9984214666002771
Metrics
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