Journal article
Impact of Six Months of Three Different Modalities of Exercise on Stress in Post-Treatment Breast Cancer Survivors
Cancers, Vol.16(19), 3398
10/04/2024
DOI: 10.3390/cancers16193398
PMCID: PMC11475836
PMID: 39410018
Abstract
Background/Objectives: Extensive evidence suggests that exercise is physically and mentally beneficial for cancer survivors. This study reports on changes in self-reported stress, physiological biomarkers for stress (salivary cortisol), and HR-QOL constructs for fifty breast cancer survivors participating in one of three different exercise programs over 6 months. Methods: Fifty post-treatment breast cancer survivors were randomized to either therapeutic yoga-based exercise (YE), comprehensive exercise (CE) (aerobic, resistance, flexibility), or choosing (C) their own exercise activities. Participants completed the Perceived Stress Scale (PSS), Medical Outcomes Short-Form 36® (SF-36), and the Pittsburgh Sleep Quality Index (PSQI). Five samples of salivary cortisol were collected on two consecutive days. The 10 samples were used to calculate the diurnal rhythm slope. Outcome measures were repeated after six months. Results: All groups improved in HR-QOL measures of PSS; PSQI sleep quality components of latency and daytime functioning; and five of the ten SF-36 scales (Mental Component Scale, Social Functioning subscale, Mental Health subscale, Physical Component Scale, Physical Functioning subscale). Although the CE group observed the most favorable change in cortisol (−0.183), where cortisol slope changes approached significance (p = 0.057), but no significant decrease in cortisol between groups were noted. Conclusion: Our results suggest that it is the engagement of, rather than the specific type of exercise, which is associated with improved HR-QOL. However, longer-term studies with better adherence monitoring and larger sample sizes are needed to better determine clinical impact.
Details
- Title: Subtitle
- Impact of Six Months of Three Different Modalities of Exercise on Stress in Post-Treatment Breast Cancer Survivors
- Creators
- Daniel C. HughesJessica Gorzelitz - University of IowaAlexis Ortiz - Allen CollegeLorenzo Cohen - The University of Texas MD Anderson Cancer CenterDorothy Long ParmaTerri Boggess - St. Mary's University, TexasNydia Tijerina Darby - Open HandShragvi BalajiAmelie G. Ramirez
- Resource Type
- Journal article
- Publication Details
- Cancers, Vol.16(19), 3398
- DOI
- 10.3390/cancers16193398
- PMID
- 39410018
- PMCID
- PMC11475836
- NLM abbreviation
- Cancers (Basel)
- ISSN
- 2072-6694
- eISSN
- 2072-6694
- Publisher
- MDPI
- Grant note
- Susan G. Komen(R): SAB08-00005 NCI-designated Cancer Center: P30CA054174 Assessment, Intervention and Measurement (AIM) Shared Resource through a Cancer Center Support Grant: CA16672
This study was funded by Susan G. Komen (R) award number SAB08-00005. The authors wish to show appreciation for Susan G. Komen (R) for funding the study. The authors acknowledge the support of the Mays Cancer Center at University of Texas Health-San Antonio, an NCI-designated Cancer Center (P30CA054174). Additionally, support was provided, in part, by the Assessment, Intervention and Measurement (AIM) Shared Resource through a Cancer Center Support Grant (CA16672, PI: P. Pisters, MD Anderson Cancer Center), from the National Cancer Institute, National Institutes of Health, and through the Duncan Family Institute for Cancer Prevention and Risk Assessment.
- Language
- English
- Date published
- 10/04/2024
- Academic Unit
- Obstetrics and Gynecology; Health, Sport, and Human Physiology
- Record Identifier
- 9984722944202771
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