Journal article
Impact of a patent ductus arteriosus on non-invasive pre- and post-ductal blood pressures in extremely preterm infants during the first two postnatal weeks
Journal of perinatology, Vol.45(3), pp.326-333
03/2025
DOI: 10.1038/s41372-025-02223-2
PMID: 39929990
Abstract
To evaluate pre- and post-ductal blood pressure (BP) in preterm infants according to patent ductus arteriosus (PDA) status obtained from targeted neonatal echocardiography (TnECHO).
Retrospective cohort study of infants born at 22-28 weeks divided according to three groups: (i) No PDA, (ii) Low volume shunt, (iii) Moderate-high volume shunt. BP parameters, demographics, and clinical characteristics were compared.
A total of 373 TnECHOs were included: 98 no PDA, 152 low volume shunt, and 123 moderate-high volume shunt. TnECHOs with no PDA had higher systolic, diastolic, and mean BP. Diastolic flow reversal in the post-ductal descending aorta was associated with lower post-ductal diastolic (p < 0.001) and mean BP (p < 0.001). Moderate-high volume shunt had higher rates of diastolic hypotension.
BP patterns varied according to PDA status. Post-ductal hypotension was more common with a moderate-high volume shunt. PDA status in this population may be the strongest influencer of BP variability.
Details
- Title: Subtitle
- Impact of a patent ductus arteriosus on non-invasive pre- and post-ductal blood pressures in extremely preterm infants during the first two postnatal weeks
- Creators
- Adrianne R Bischoff - University of IowaAmy A Hobson - University of IowaPatrick J McNamara - University of IowaDanielle R Rios - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Journal of perinatology, Vol.45(3), pp.326-333
- Publisher
- SPRINGERNATURE
- DOI
- 10.1038/s41372-025-02223-2
- PMID
- 39929990
- ISSN
- 0743-8346
- eISSN
- 1476-5543
- Grant note
- NIHCTSA: UM1TR004403
The authors have no financial relationships relevant to this article to disclose. NIH and CTSA grant number UM1TR004403 for REDCap use.
- Language
- English
- Electronic publication date
- 02/10/2025
- Date published
- 03/2025
- Academic Unit
- Stead Family Department of Pediatrics; Neonatology; Internal Medicine
- Record Identifier
- 9984790975802771
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