Journal article
Impact of annual operator and institutional volume on percutaneous coronary intervention outcomes: a 5-year United States experience (2005-2009)
Circulation (New York, N.Y.), Vol.130(16), pp.1392-1406
10/14/2014
DOI: 10.1161/CIRCULATIONAHA.114.009281
PMID: 25189214
Abstract
The relationship between operator or institutional volume and outcomes among patients undergoing percutaneous coronary interventions (PCI) is unclear.
Cross-sectional study based on the Healthcare Cost and Utilization Project's Nationwide Inpatient Sample between 2005 to 2009. Subjects were identified by International Classification of Diseases, 9(th) Revision, Clinical Modification procedure code, 36.06 and 36.07. Annual operator and institutional volumes were calculated using unique identification numbers and then divided into quartiles. Three-level hierarchical multivariate mixed models were created. The primary outcome was in-hospital mortality; secondary outcome was a composite of in-hospital mortality and peri-procedural complications. A total of 457,498 PCIs were identified representing a total of 2,243,209 PCIs performed in the United States during the study period. In-hospital, all-cause mortality was 1.08%, and the overall complication rate was 7.10%. The primary and secondary outcomes of procedures performed by operators in 4(th) [annual procedural volume; primary and secondary outcomes] [>100; 0.59% and 5.51%], 3(rd) [45-100; 0.87% and 6.40%], and 2(nd) quartile [16-44; 1.15% and 7.75%] were significantly less (P<0.001) when compared with those by operators in the 1(st) quartile [≤15; 1.68% and 10.91%]. Spline analysis also showed significant operator and institutional volume outcome relationship. Similarly operators in the higher quartiles witnessed a significant reduction in length of hospital stay and cost of hospitalization (P<0.001).
Overall in-hospital mortality after PCI was low. An increase in operator and institutional volume of PCI was found to be associated with a decrease in adverse outcomes, length of hospital stay, and cost of hospitalization.
Details
- Title: Subtitle
- Impact of annual operator and institutional volume on percutaneous coronary intervention outcomes: a 5-year United States experience (2005-2009)
- Creators
- Apurva O Badheka - From Yale New Haven Medical Center, New Haven, CT (A.O.B.); Staten Island University Hospital, Staten Island, NY (N.J.P., N.S., F.V.T.); UMass Memorial Medical Center, Worcester, MA (P.G.); University of Miami Miller School of Medicine, Miami, FL (V.S., G.T.S., E.D.M., M.G.C.); Saint Peter's University Hospital, New Brunswick, NJ (N.P.); Mount Sinai's St Luke Roosevelt Hospital Center, New York, NY (S.A.); MedStar Washington Hospital Center, Washington, DC (A.C.); UPMC Shadyside Hospital, Pittsburgh, PA (K.M.); University of Arkansas, Little Rock, AR (A.D.); Icahn School of Medicine at Mount Sinai, New York, NY (A.P.); Detroit Medical Center, Detroit, MI (S.S.P., M.B., T.M., T.S., C.L.G.); Cedar-Sinai Medical Center, Los Angeles, CA (A.R., S.K., R.M.); Henry Ford Hospital, Detroit, MI (W.W.O.); Mayo Clinic, Rochester, MN (C.S.R.). apurva.badheka@yale.eduNileshkumar J Patel - From Yale New Haven Medical Center, New Haven, CT (A.O.B.); Staten Island University Hospital, Staten Island, NY (N.J.P., N.S., F.V.T.); UMass Memorial Medical Center, Worcester, MA (P.G.); University of Miami Miller School of Medicine, Miami, FL (V.S., G.T.S., E.D.M., M.G.C.); Saint Peter's University Hospital, New Brunswick, NJ (N.P.); Mount Sinai's St Luke Roosevelt Hospital Center, New York, NY (S.A.); MedStar Washington Hospital Center, Washington, DC (A.C.); UPMC Shadyside Hospital, Pittsburgh, PA (K.M.); University of Arkansas, Little Rock, AR (A.D.); Icahn School of Medicine at Mount Sinai, New York, NY (A.P.); Detroit Medical Center, Detroit, MI (S.S.P., M.B., T.M., T.S., C.L.G.); Cedar-Sinai Medical Center, Los Angeles, CA (A.R., S.K., R.M.); Henry Ford Hospital, Detroit, MI (W.W.O.); Mayo Clinic, Rochester, MN (C.S.R.)Peeyush Grover - From Yale New Haven Medical Center, New Haven, CT (A.O.B.); Staten Island University Hospital, Staten Island, NY (N.J.P., N.S., F.V.T.); UMass Memorial Medical Center, Worcester, MA (P.G.); University of Miami Miller School of Medicine, Miami, FL (V.S., G.T.S., E.D.M., M.G.C.); Saint Peter's University Hospital, New Brunswick, NJ (N.P.); Mount Sinai's St Luke Roosevelt Hospital Center, New York, NY (S.A.); MedStar Washington Hospital Center, Washington, DC (A.C.); UPMC Shadyside Hospital, Pittsburgh, PA (K.M.); University of Arkansas, Little Rock, AR (A.D.); Icahn School of Medicine at Mount Sinai, New York, NY (A.P.); Detroit Medical Center, Detroit, MI (S.S.P., M.B., T.M., T.S., C.L.G.); Cedar-Sinai Medical Center, Los Angeles, CA (A.R., S.K., R.M.); Henry Ford Hospital, Detroit, MI (W.W.O.); Mayo Clinic, Rochester, MN (C.S.R.)Vikas Singh - From Yale New Haven Medical Center, New Haven, CT (A.O.B.); Staten Island University Hospital, Staten Island, NY (N.J.P., N.S., F.V.T.); UMass Memorial Medical Center, Worcester, MA (P.G.); University of Miami Miller School of Medicine, Miami, FL (V.S., G.T.S., E.D.M., M.G.C.); Saint Peter's University Hospital, New Brunswick, NJ (N.P.); Mount Sinai's St Luke Roosevelt Hospital Center, New York, NY (S.A.); MedStar Washington Hospital Center, Washington, DC (A.C.); UPMC Shadyside Hospital, Pittsburgh, PA (K.M.); University of Arkansas, Little Rock, AR (A.D.); Icahn School of Medicine at Mount Sinai, New York, NY (A.P.); Detroit Medical Center, Detroit, MI (S.S.P., M.B., T.M., T.S., C.L.G.); Cedar-Sinai Medical Center, Los Angeles, CA (A.R., S.K., R.M.); Henry Ford Hospital, Detroit, MI (W.W.O.); Mayo Clinic, Rochester, MN (C.S.R.)Nilay Patel - From Yale New Haven Medical Center, New Haven, CT (A.O.B.); Staten Island University Hospital, Staten Island, NY (N.J.P., N.S., F.V.T.); UMass Memorial Medical Center, Worcester, MA (P.G.); University of Miami Miller School of Medicine, Miami, FL (V.S., G.T.S., E.D.M., M.G.C.); Saint Peter's University Hospital, New Brunswick, NJ (N.P.); Mount Sinai's St Luke Roosevelt Hospital Center, New York, NY (S.A.); MedStar Washington Hospital Center, Washington, DC (A.C.); UPMC Shadyside Hospital, Pittsburgh, PA (K.M.); University of Arkansas, Little Rock, AR (A.D.); Icahn School of Medicine at Mount Sinai, New York, NY (A.P.); Detroit Medical Center, Detroit, MI (S.S.P., M.B., T.M., T.S., C.L.G.); Cedar-Sinai Medical Center, Los Angeles, CA (A.R., S.K., R.M.); Henry Ford Hospital, Detroit, MI (W.W.O.); Mayo Clinic, Rochester, MN (C.S.R.)Shilpkumar Arora - From Yale New Haven Medical Center, New Haven, CT (A.O.B.); Staten Island University Hospital, Staten Island, NY (N.J.P., N.S., F.V.T.); UMass Memorial Medical Center, Worcester, MA (P.G.); University of Miami Miller School of Medicine, Miami, FL (V.S., G.T.S., E.D.M., M.G.C.); Saint Peter's University Hospital, New Brunswick, NJ (N.P.); Mount Sinai's St Luke Roosevelt Hospital Center, New York, NY (S.A.); MedStar Washington Hospital Center, Washington, DC (A.C.); UPMC Shadyside Hospital, Pittsburgh, PA (K.M.); University of Arkansas, Little Rock, AR (A.D.); Icahn School of Medicine at Mount Sinai, New York, NY (A.P.); Detroit Medical Center, Detroit, MI (S.S.P., M.B., T.M., T.S., C.L.G.); Cedar-Sinai Medical Center, Los Angeles, CA (A.R., S.K., R.M.); Henry Ford Hospital, Detroit, MI (W.W.O.); Mayo Clinic, Rochester, MN (C.S.R.)Ankit Chothani - From Yale New Haven Medical Center, New Haven, CT (A.O.B.); Staten Island University Hospital, Staten Island, NY (N.J.P., N.S., F.V.T.); UMass Memorial Medical Center, Worcester, MA (P.G.); University of Miami Miller School of Medicine, Miami, FL (V.S., G.T.S., E.D.M., M.G.C.); Saint Peter's University Hospital, New Brunswick, NJ (N.P.); Mount Sinai's St Luke Roosevelt Hospital Center, New York, NY (S.A.); MedStar Washington Hospital Center, Washington, DC (A.C.); UPMC Shadyside Hospital, Pittsburgh, PA (K.M.); University of Arkansas, Little Rock, AR (A.D.); Icahn School of Medicine at Mount Sinai, New York, NY (A.P.); Detroit Medical Center, Detroit, MI (S.S.P., M.B., T.M., T.S., C.L.G.); Cedar-Sinai Medical Center, Los Angeles, CA (A.R., S.K., R.M.); Henry Ford Hospital, Detroit, MI (W.W.O.); Mayo Clinic, Rochester, MN (C.S.R.)Kathan Mehta - From Yale New Haven Medical Center, New Haven, CT (A.O.B.); Staten Island University Hospital, Staten Island, NY (N.J.P., N.S., F.V.T.); UMass Memorial Medical Center, Worcester, MA (P.G.); University of Miami Miller School of Medicine, Miami, FL (V.S., G.T.S., E.D.M., M.G.C.); Saint Peter's University Hospital, New Brunswick, NJ (N.P.); Mount Sinai's St Luke Roosevelt Hospital Center, New York, NY (S.A.); MedStar Washington Hospital Center, Washington, DC (A.C.); UPMC Shadyside Hospital, Pittsburgh, PA (K.M.); University of Arkansas, Little Rock, AR (A.D.); Icahn School of Medicine at Mount Sinai, New York, NY (A.P.); Detroit Medical Center, Detroit, MI (S.S.P., M.B., T.M., T.S., C.L.G.); Cedar-Sinai Medical Center, Los Angeles, CA (A.R., S.K., R.M.); Henry Ford Hospital, Detroit, MI (W.W.O.); Mayo Clinic, Rochester, MN (C.S.R.)Abhishek Deshmukh - From Yale New Haven Medical Center, New Haven, CT (A.O.B.); Staten Island University Hospital, Staten Island, NY (N.J.P., N.S., F.V.T.); UMass Memorial Medical Center, Worcester, MA (P.G.); University of Miami Miller School of Medicine, Miami, FL (V.S., G.T.S., E.D.M., M.G.C.); Saint Peter's University Hospital, New Brunswick, NJ (N.P.); Mount Sinai's St Luke Roosevelt Hospital Center, New York, NY (S.A.); MedStar Washington Hospital Center, Washington, DC (A.C.); UPMC Shadyside Hospital, Pittsburgh, PA (K.M.); University of Arkansas, Little Rock, AR (A.D.); Icahn School of Medicine at Mount Sinai, New York, NY (A.P.); Detroit Medical Center, Detroit, MI (S.S.P., M.B., T.M., T.S., C.L.G.); Cedar-Sinai Medical Center, Los Angeles, CA (A.R., S.K., R.M.); Henry Ford Hospital, Detroit, MI (W.W.O.); Mayo Clinic, Rochester, MN (C.S.R.)Ghanshyambhai T Savani - From Yale New Haven Medical Center, New Haven, CT (A.O.B.); Staten Island University Hospital, Staten Island, NY (N.J.P., N.S., F.V.T.); UMass Memorial Medical Center, Worcester, MA (P.G.); University of Miami Miller School of Medicine, Miami, FL (V.S., G.T.S., E.D.M., M.G.C.); Saint Peter's University Hospital, New Brunswick, NJ (N.P.); Mount Sinai's St Luke Roosevelt Hospital Center, New York, NY (S.A.); MedStar Washington Hospital Center, Washington, DC (A.C.); UPMC Shadyside Hospital, Pittsburgh, PA (K.M.); University of Arkansas, Little Rock, AR (A.D.); Icahn School of Medicine at Mount Sinai, New York, NY (A.P.); Detroit Medical Center, Detroit, MI (S.S.P., M.B., T.M., T.S., C.L.G.); Cedar-Sinai Medical Center, Los Angeles, CA (A.R., S.K., R.M.); Henry Ford Hospital, Detroit, MI (W.W.O.); Mayo Clinic, Rochester, MN (C.S.R.)Achint Patel - From Yale New Haven Medical Center, New Haven, CT (A.O.B.); Staten Island University Hospital, Staten Island, NY (N.J.P., N.S., F.V.T.); UMass Memorial Medical Center, Worcester, MA (P.G.); University of Miami Miller School of Medicine, Miami, FL (V.S., G.T.S., E.D.M., M.G.C.); Saint Peter's University Hospital, New Brunswick, NJ (N.P.); Mount Sinai's St Luke Roosevelt Hospital Center, New York, NY (S.A.); MedStar Washington Hospital Center, Washington, DC (A.C.); UPMC Shadyside Hospital, Pittsburgh, PA (K.M.); University of Arkansas, Little Rock, AR (A.D.); Icahn School of Medicine at Mount Sinai, New York, NY (A.P.); Detroit Medical Center, Detroit, MI (S.S.P., M.B., T.M., T.S., C.L.G.); Cedar-Sinai Medical Center, Los Angeles, CA (A.R., S.K., R.M.); Henry Ford Hospital, Detroit, MI (W.W.O.); Mayo Clinic, Rochester, MN (C.S.R.)Sidakpal S Panaich - From Yale New Haven Medical Center, New Haven, CT (A.O.B.); Staten Island University Hospital, Staten Island, NY (N.J.P., N.S., F.V.T.); UMass Memorial Medical Center, Worcester, MA (P.G.); University of Miami Miller School of Medicine, Miami, FL (V.S., G.T.S., E.D.M., M.G.C.); Saint Peter's University Hospital, New Brunswick, NJ (N.P.); Mount Sinai's St Luke Roosevelt Hospital Center, New York, NY (S.A.); MedStar Washington Hospital Center, Washington, DC (A.C.); UPMC Shadyside Hospital, Pittsburgh, PA (K.M.); University of Arkansas, Little Rock, AR (A.D.); Icahn School of Medicine at Mount Sinai, New York, NY (A.P.); Detroit Medical Center, Detroit, MI (S.S.P., M.B., T.M., T.S., C.L.G.); Cedar-Sinai Medical Center, Los Angeles, CA (A.R., S.K., R.M.); Henry Ford Hospital, Detroit, MI (W.W.O.); Mayo Clinic, Rochester, MN (C.S.R.)Neeraj Shah - From Yale New Haven Medical Center, New Haven, CT (A.O.B.); Staten Island University Hospital, Staten Island, NY (N.J.P., N.S., F.V.T.); UMass Memorial Medical Center, Worcester, MA (P.G.); University of Miami Miller School of Medicine, Miami, FL (V.S., G.T.S., E.D.M., M.G.C.); Saint Peter's University Hospital, New Brunswick, NJ (N.P.); Mount Sinai's St Luke Roosevelt Hospital Center, New York, NY (S.A.); MedStar Washington Hospital Center, Washington, DC (A.C.); UPMC Shadyside Hospital, Pittsburgh, PA (K.M.); University of Arkansas, Little Rock, AR (A.D.); Icahn School of Medicine at Mount Sinai, New York, NY (A.P.); Detroit Medical Center, Detroit, MI (S.S.P., M.B., T.M., T.S., C.L.G.); Cedar-Sinai Medical Center, Los Angeles, CA (A.R., S.K., R.M.); Henry Ford Hospital, Detroit, MI (W.W.O.); Mayo Clinic, Rochester, MN (C.S.R.)Ankit Rathod - From Yale New Haven Medical Center, New Haven, CT (A.O.B.); Staten Island University Hospital, Staten Island, NY (N.J.P., N.S., F.V.T.); UMass Memorial Medical Center, Worcester, MA (P.G.); University of Miami Miller School of Medicine, Miami, FL (V.S., G.T.S., E.D.M., M.G.C.); Saint Peter's University Hospital, New Brunswick, NJ (N.P.); Mount Sinai's St Luke Roosevelt Hospital Center, New York, NY (S.A.); MedStar Washington Hospital Center, Washington, DC (A.C.); UPMC Shadyside Hospital, Pittsburgh, PA (K.M.); University of Arkansas, Little Rock, AR (A.D.); Icahn School of Medicine at Mount Sinai, New York, NY (A.P.); Detroit Medical Center, Detroit, MI (S.S.P., M.B., T.M., T.S., C.L.G.); Cedar-Sinai Medical Center, Los Angeles, CA (A.R., S.K., R.M.); Henry Ford Hospital, Detroit, MI (W.W.O.); Mayo Clinic, Rochester, MN (C.S.R.)Michael Brown - From Yale New Haven Medical Center, New Haven, CT (A.O.B.); Staten Island University Hospital, Staten Island, NY (N.J.P., N.S., F.V.T.); UMass Memorial Medical Center, Worcester, MA (P.G.); University of Miami Miller School of Medicine, Miami, FL (V.S., G.T.S., E.D.M., M.G.C.); Saint Peter's University Hospital, New Brunswick, NJ (N.P.); Mount Sinai's St Luke Roosevelt Hospital Center, New York, NY (S.A.); MedStar Washington Hospital Center, Washington, DC (A.C.); UPMC Shadyside Hospital, Pittsburgh, PA (K.M.); University of Arkansas, Little Rock, AR (A.D.); Icahn School of Medicine at Mount Sinai, New York, NY (A.P.); Detroit Medical Center, Detroit, MI (S.S.P., M.B., T.M., T.S., C.L.G.); Cedar-Sinai Medical Center, Los Angeles, CA (A.R., S.K., R.M.); Henry Ford Hospital, Detroit, MI (W.W.O.); Mayo Clinic, Rochester, MN (C.S.R.)Tamam Mohamad - From Yale New Haven Medical Center, New Haven, CT (A.O.B.); Staten Island University Hospital, Staten Island, NY (N.J.P., N.S., F.V.T.); UMass Memorial Medical Center, Worcester, MA (P.G.); University of Miami Miller School of Medicine, Miami, FL (V.S., G.T.S., E.D.M., M.G.C.); Saint Peter's University Hospital, New Brunswick, NJ (N.P.); Mount Sinai's St Luke Roosevelt Hospital Center, New York, NY (S.A.); MedStar Washington Hospital Center, Washington, DC (A.C.); UPMC Shadyside Hospital, Pittsburgh, PA (K.M.); University of Arkansas, Little Rock, AR (A.D.); Icahn School of Medicine at Mount Sinai, New York, NY (A.P.); Detroit Medical Center, Detroit, MI (S.S.P., M.B., T.M., T.S., C.L.G.); Cedar-Sinai Medical Center, Los Angeles, CA (A.R., S.K., R.M.); Henry Ford Hospital, Detroit, MI (W.W.O.); Mayo Clinic, Rochester, MN (C.S.R.)Frank V Tamburrino - From Yale New Haven Medical Center, New Haven, CT (A.O.B.); Staten Island University Hospital, Staten Island, NY (N.J.P., N.S., F.V.T.); UMass Memorial Medical Center, Worcester, MA (P.G.); University of Miami Miller School of Medicine, Miami, FL (V.S., G.T.S., E.D.M., M.G.C.); Saint Peter's University Hospital, New Brunswick, NJ (N.P.); Mount Sinai's St Luke Roosevelt Hospital Center, New York, NY (S.A.); MedStar Washington Hospital Center, Washington, DC (A.C.); UPMC Shadyside Hospital, Pittsburgh, PA (K.M.); University of Arkansas, Little Rock, AR (A.D.); Icahn School of Medicine at Mount Sinai, New York, NY (A.P.); Detroit Medical Center, Detroit, MI (S.S.P., M.B., T.M., T.S., C.L.G.); Cedar-Sinai Medical Center, Los Angeles, CA (A.R., S.K., R.M.); Henry Ford Hospital, Detroit, MI (W.W.O.); Mayo Clinic, Rochester, MN (C.S.R.)Saibal Kar - From Yale New Haven Medical Center, New Haven, CT (A.O.B.); Staten Island University Hospital, Staten Island, NY (N.J.P., N.S., F.V.T.); UMass Memorial Medical Center, Worcester, MA (P.G.); University of Miami Miller School of Medicine, Miami, FL (V.S., G.T.S., E.D.M., M.G.C.); Saint Peter's University Hospital, New Brunswick, NJ (N.P.); Mount Sinai's St Luke Roosevelt Hospital Center, New York, NY (S.A.); MedStar Washington Hospital Center, Washington, DC (A.C.); UPMC Shadyside Hospital, Pittsburgh, PA (K.M.); University of Arkansas, Little Rock, AR (A.D.); Icahn School of Medicine at Mount Sinai, New York, NY (A.P.); Detroit Medical Center, Detroit, MI (S.S.P., M.B., T.M., T.S., C.L.G.); Cedar-Sinai Medical Center, Los Angeles, CA (A.R., S.K., R.M.); Henry Ford Hospital, Detroit, MI (W.W.O.); Mayo Clinic, Rochester, MN (C.S.R.)Raj Makkar - From Yale New Haven Medical Center, New Haven, CT (A.O.B.); Staten Island University Hospital, Staten Island, NY (N.J.P., N.S., F.V.T.); UMass Memorial Medical Center, Worcester, MA (P.G.); University of Miami Miller School of Medicine, Miami, FL (V.S., G.T.S., E.D.M., M.G.C.); Saint Peter's University Hospital, New Brunswick, NJ (N.P.); Mount Sinai's St Luke Roosevelt Hospital Center, New York, NY (S.A.); MedStar Washington Hospital Center, Washington, DC (A.C.); UPMC Shadyside Hospital, Pittsburgh, PA (K.M.); University of Arkansas, Little Rock, AR (A.D.); Icahn School of Medicine at Mount Sinai, New York, NY (A.P.); Detroit Medical Center, Detroit, MI (S.S.P., M.B., T.M., T.S., C.L.G.); Cedar-Sinai Medical Center, Los Angeles, CA (A.R., S.K., R.M.); Henry Ford Hospital, Detroit, MI (W.W.O.); Mayo Clinic, Rochester, MN (C.S.R.)William W O'Neill - From Yale New Haven Medical Center, New Haven, CT (A.O.B.); Staten Island University Hospital, Staten Island, NY (N.J.P., N.S., F.V.T.); UMass Memorial Medical Center, Worcester, MA (P.G.); University of Miami Miller School of Medicine, Miami, FL (V.S., G.T.S., E.D.M., M.G.C.); Saint Peter's University Hospital, New Brunswick, NJ (N.P.); Mount Sinai's St Luke Roosevelt Hospital Center, New York, NY (S.A.); MedStar Washington Hospital Center, Washington, DC (A.C.); UPMC Shadyside Hospital, Pittsburgh, PA (K.M.); University of Arkansas, Little Rock, AR (A.D.); Icahn School of Medicine at Mount Sinai, New York, NY (A.P.); Detroit Medical Center, Detroit, MI (S.S.P., M.B., T.M., T.S., C.L.G.); Cedar-Sinai Medical Center, Los Angeles, CA (A.R., S.K., R.M.); Henry Ford Hospital, Detroit, MI (W.W.O.); Mayo Clinic, Rochester, MN (C.S.R.)Eduardo De Marchena - From Yale New Haven Medical Center, New Haven, CT (A.O.B.); Staten Island University Hospital, Staten Island, NY (N.J.P., N.S., F.V.T.); UMass Memorial Medical Center, Worcester, MA (P.G.); University of Miami Miller School of Medicine, Miami, FL (V.S., G.T.S., E.D.M., M.G.C.); Saint Peter's University Hospital, New Brunswick, NJ (N.P.); Mount Sinai's St Luke Roosevelt Hospital Center, New York, NY (S.A.); MedStar Washington Hospital Center, Washington, DC (A.C.); UPMC Shadyside Hospital, Pittsburgh, PA (K.M.); University of Arkansas, Little Rock, AR (A.D.); Icahn School of Medicine at Mount Sinai, New York, NY (A.P.); Detroit Medical Center, Detroit, MI (S.S.P., M.B., T.M., T.S., C.L.G.); Cedar-Sinai Medical Center, Los Angeles, CA (A.R., S.K., R.M.); Henry Ford Hospital, Detroit, MI (W.W.O.); Mayo Clinic, Rochester, MN (C.S.R.)Theodore Schreiber - From Yale New Haven Medical Center, New Haven, CT (A.O.B.); Staten Island University Hospital, Staten Island, NY (N.J.P., N.S., F.V.T.); UMass Memorial Medical Center, Worcester, MA (P.G.); University of Miami Miller School of Medicine, Miami, FL (V.S., G.T.S., E.D.M., M.G.C.); Saint Peter's University Hospital, New Brunswick, NJ (N.P.); Mount Sinai's St Luke Roosevelt Hospital Center, New York, NY (S.A.); MedStar Washington Hospital Center, Washington, DC (A.C.); UPMC Shadyside Hospital, Pittsburgh, PA (K.M.); University of Arkansas, Little Rock, AR (A.D.); Icahn School of Medicine at Mount Sinai, New York, NY (A.P.); Detroit Medical Center, Detroit, MI (S.S.P., M.B., T.M., T.S., C.L.G.); Cedar-Sinai Medical Center, Los Angeles, CA (A.R., S.K., R.M.); Henry Ford Hospital, Detroit, MI (W.W.O.); Mayo Clinic, Rochester, MN (C.S.R.)Cindy L Grines - From Yale New Haven Medical Center, New Haven, CT (A.O.B.); Staten Island University Hospital, Staten Island, NY (N.J.P., N.S., F.V.T.); UMass Memorial Medical Center, Worcester, MA (P.G.); University of Miami Miller School of Medicine, Miami, FL (V.S., G.T.S., E.D.M., M.G.C.); Saint Peter's University Hospital, New Brunswick, NJ (N.P.); Mount Sinai's St Luke Roosevelt Hospital Center, New York, NY (S.A.); MedStar Washington Hospital Center, Washington, DC (A.C.); UPMC Shadyside Hospital, Pittsburgh, PA (K.M.); University of Arkansas, Little Rock, AR (A.D.); Icahn School of Medicine at Mount Sinai, New York, NY (A.P.); Detroit Medical Center, Detroit, MI (S.S.P., M.B., T.M., T.S., C.L.G.); Cedar-Sinai Medical Center, Los Angeles, CA (A.R., S.K., R.M.); Henry Ford Hospital, Detroit, MI (W.W.O.); Mayo Clinic, Rochester, MN (C.S.R.)Charanjit S Rihal - From Yale New Haven Medical Center, New Haven, CT (A.O.B.); Staten Island University Hospital, Staten Island, NY (N.J.P., N.S., F.V.T.); UMass Memorial Medical Center, Worcester, MA (P.G.); University of Miami Miller School of Medicine, Miami, FL (V.S., G.T.S., E.D.M., M.G.C.); Saint Peter's University Hospital, New Brunswick, NJ (N.P.); Mount Sinai's St Luke Roosevelt Hospital Center, New York, NY (S.A.); MedStar Washington Hospital Center, Washington, DC (A.C.); UPMC Shadyside Hospital, Pittsburgh, PA (K.M.); University of Arkansas, Little Rock, AR (A.D.); Icahn School of Medicine at Mount Sinai, New York, NY (A.P.); Detroit Medical Center, Detroit, MI (S.S.P., M.B., T.M., T.S., C.L.G.); Cedar-Sinai Medical Center, Los Angeles, CA (A.R., S.K., R.M.); Henry Ford Hospital, Detroit, MI (W.W.O.); Mayo Clinic, Rochester, MN (C.S.R.)Mauricio G Cohen - From Yale New Haven Medical Center, New Haven, CT (A.O.B.); Staten Island University Hospital, Staten Island, NY (N.J.P., N.S., F.V.T.); UMass Memorial Medical Center, Worcester, MA (P.G.); University of Miami Miller School of Medicine, Miami, FL (V.S., G.T.S., E.D.M., M.G.C.); Saint Peter's University Hospital, New Brunswick, NJ (N.P.); Mount Sinai's St Luke Roosevelt Hospital Center, New York, NY (S.A.); MedStar Washington Hospital Center, Washington, DC (A.C.); UPMC Shadyside Hospital, Pittsburgh, PA (K.M.); University of Arkansas, Little Rock, AR (A.D.); Icahn School of Medicine at Mount Sinai, New York, NY (A.P.); Detroit Medical Center, Detroit, MI (S.S.P., M.B., T.M., T.S., C.L.G.); Cedar-Sinai Medical Center, Los Angeles, CA (A.R., S.K., R.M.); Henry Ford Hospital, Detroit, MI (W.W.O.); Mayo Clinic, Rochester, MN (C.S.R.)
- Resource Type
- Journal article
- Publication Details
- Circulation (New York, N.Y.), Vol.130(16), pp.1392-1406
- DOI
- 10.1161/CIRCULATIONAHA.114.009281
- PMID
- 25189214
- NLM abbreviation
- Circulation
- ISSN
- 0009-7322
- eISSN
- 1524-4539
- Publisher
- Lippincott Williams & Wilkins
- Language
- English
- Date published
- 10/14/2014
- Academic Unit
- Cardiovascular Medicine; Internal Medicine
- Record Identifier
- 9984094356102771
Metrics
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