Journal article
Impact of bleeding complications on length of stay and critical care utilization in cardiac surgery patients in England
Journal of cardiothoracic surgery, Vol.14(1), pp.64-64
04/02/2019
DOI: 10.1186/s13019-019-0881-3
PMCID: PMC6444533
PMID: 30940172
Abstract
Background: Bleeding is a significant complication in cardiac surgery and is associated with substantial morbidity and mortality. This study evaluated the impact of bleeding on length of stay (LOS) and critical care utilization in a nationwide sample of cardiac surgery patients treated at English hospitals. Methods: Retrospective, observational cohort study using linked English Hospital Episode Statistics (HES) and Clinical Practice Research Datalink (CPRD) records for a nationwide sample of patients aged ≥18 years who underwent coronary artery bypass graft (CABG), valve repair/replacement, or aortic operations from January 2010 through February 2016. The primary independent variables were in-hospital bleeding complications and reoperation for bleeding before discharge. Generalized linear models were used to quantify the adjusted mean incremental difference [MID] in post-procedure LOS and critical care days associated with bleeding complications, independent of measured baseline characteristics. Results: The study included 7774 cardiac surgery patients (3963 CABG; 2363 valve replacement/repair; 160 aortic procedures; 1288 multiple procedures, primarily CABG+valve). Mean LOS was 10.7d, including a mean of 4.2d in critical care. Incidences of in-hospital bleeding complications and reoperation for bleeding were 6.7 and 0.3%, respectively. Patients with bleeding had longer LOS (MID: 3.1d; p < 0.0001) and spent more days in critical care (MID: 2.4d; p < 0.0001). Reoperation for bleeding was associated with larger increases in LOS (MID = 4.0d; p = 0.002) and days in critical care (MID = 3.2d; p = 0.001). Conclusions: Among English cardiac surgery patients, in-hospital bleeding complications were associated with substantial increases in healthcare utilization. Increased use of evidence-based strategies to prevent and manage bleeding may reduce the clinical and economic burden associated with bleeding complications in cardiac surgery.
Details
- Title: Subtitle
- Impact of bleeding complications on length of stay and critical care utilization in cardiac surgery patients in England
- Creators
- Nawwar Al-Attar - Golden Jubilee National HospitalStephen Johnston - Johnson & Johnson (United States)Nadine Jamous - Johnson & Johnson (United Kingdom)Sameer Mistry - Johnson & Johnson (United Kingdom)Ena GhoshGaurav Gangoli - Ethicon Inc.Walter Danker - Ethicon Inc.Katherine Etter - Johnson & Johnson (United States)Eric Ammann - Johnson & Johnson (United States)
- Resource Type
- Journal article
- Publication Details
- Journal of cardiothoracic surgery, Vol.14(1), pp.64-64
- DOI
- 10.1186/s13019-019-0881-3
- PMID
- 30940172
- PMCID
- PMC6444533
- NLM abbreviation
- J Cardiothorac Surg
- ISSN
- 1749-8090
- eISSN
- 1749-8090
- Publisher
- BioMed Central
- Grant note
- ;
- Language
- English
- Date published
- 04/02/2019
- Academic Unit
- Epidemiology
- Record Identifier
- 9984363667902771
Metrics
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