Journal article
Impact of central venous catheter repair in pediatric intestinal failure
JPEN. Journal of parenteral and enteral nutrition, Vol.46(1), pp.222-228
01/2022
DOI: 10.1002/jpen.2109
PMID: 33734463
Abstract
Patients with intestinal failure (IF) require long-term parenteral nutrition through central venous catheters (CVCs). When damaged, catheter replacement or repair is considered. Limited literature exists on repair outcomes in this population. We aimed to assess the impact of repair on durability of exiting CVCs and infection rates.
This was a retrospective cohort study of pediatric IF patients with tunneled silicone CVCs over 10 years. Outcomes were evaluated by assessing CVC longevity, repair success, replacement, and postrepair infection rates.
One hundred thirty-eight repairs and 45 replacements were conducted in 37 patients with repair and replacement rates of 4.7 and 1.5 per 1000 catheter days, respectively. Twenty patients (54%) required ≥1 repair. For CVCs requiring repair, median CVC durability without and with repairs were at 123 and 391 days, respectively (P < .0001). Overall repair success rate was 96% with significantly lower success in the emergency department at 81% (P = .007). The 7-day postrepair infection rate was 2.2% without specific risk factors identified. Most repairs (76%) were performed by the Pediatric Gastroenterology division. Variability in practice was noted among services, including frequency of periprocedural antibiotic use and performance of temporary repairs before permanent repairs. A gradual increase in CVC repair rate was noted over time.
Our study showed that CVC repair is effective in prolonging CVC durability in pediatric IF patients without increasing infection rates. Incorporating a temporary repair as a step before permanent repair may offer a route to address potential intraluminal thrombosis before permanent repair.
Details
- Title: Subtitle
- Impact of central venous catheter repair in pediatric intestinal failure
- Creators
- Velarchana Santhana - Roy J. and Lucille A. Carver College of MedicineMary Beth Davis - University of Iowa Stead Family Children’s HospitalRiad Rahhal - University of Iowa
- Resource Type
- Journal article
- Publication Details
- JPEN. Journal of parenteral and enteral nutrition, Vol.46(1), pp.222-228
- DOI
- 10.1002/jpen.2109
- PMID
- 33734463
- ISSN
- 0148-6071
- eISSN
- 1941-2444
- Language
- English
- Date published
- 01/2022
- Academic Unit
- Stead Family Department of Pediatrics; Nursing; Gastroenterology, Hepatology, Pancreatology, and Nutrition
- Record Identifier
- 9984354156102771
Metrics
18 Record Views