Impact of metagenomic next-generation sequencing on clinical decision-making at an academic medical center, a retrospective study, Iowa, 2020–2022

Michael Olthoff; Takaaki Kobayashi; Meredith Parsons; Bradley Ford; Kunatum Prasidthrathsint; Lemuel Non; Jorge Salinas; Daniel Diekema; Dilek Ince

doi:10.1017/ash.2024.31

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Impact of metagenomic next-generation sequencing on clinical decision-making at an academic medical center, a retrospective study, Iowa, 2020–2022

Journal article

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Peer reviewed

Impact of metagenomic next-generation sequencing on clinical decision-making at an academic medical center, a retrospective study, Iowa, 2020–2022

Michael Olthoff, Takaaki Kobayashi, Meredith Parsons, Bradley Ford, Kunatum Prasidthrathsint, Lemuel Non, Jorge Salinas, Daniel Diekema and Dilek Ince

Antimicrobial stewardship & healthcare epidemiology : ASHE, Vol.4(1), e39

03/27/2024

DOI: 10.1017/ash.2024.31

PMCID: PMC10983051

PMID: 38562514

Appears in UI Libraries Support Open Access

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Abstract

We assessed the impact of metagenomic next-generation sequencing (mNGS) on patient care using previously established criteria. Among 37 patients receiving mNGS testing, 16% showed results that had a positive clinical impact. While mNGS results may offer valuable supplementary information, results should be interpreted within the broader clinical context and evaluation.

Epstein-Barr Virus

Infectious Diseases

Tuberculosis

Human papillomavirus

UIOWA OA Agreement

Details

Title: Subtitle: Impact of metagenomic next-generation sequencing on clinical decision-making at an academic medical center, a retrospective study, Iowa, 2020–2022
Creators: Michael Olthoff
Takaaki Kobayashi
Meredith Parsons
Bradley Ford
Kunatum Prasidthrathsint
Lemuel Non
Jorge Salinas - Stanford University
Daniel Diekema
Dilek Ince
Resource Type: Journal article
Publication Details: Antimicrobial stewardship & healthcare epidemiology : ASHE, Vol.4(1), e39
DOI: 10.1017/ash.2024.31
PMID: 38562514
PMCID: PMC10983051
NLM abbreviation: Antimicrob Steward Healthc Epidemiol
eISSN: 2732-494X
Publisher: Cambridge University Press
Language: English
Date published: 03/27/2024
Academic Unit: Infectious Diseases; Pathology; Internal Medicine
Record Identifier: 9984577036302771

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