Impact of the AYA HOPE Comorbidity Index on Assessing Health Care Service Needs and Health Status among Adolescents and Young Adults with Cancer

Xiao-Cheng Wu; Pinki K Prasad; Ian Landry; Linda C Harlan; Helen M Parsons; Charles F Lynch; Ashley W Smith; Ann S Hamilton; Theresa H M Keegan; AYA HOPE Study Collaborative Group

doi:10.1158/1055-9965.EPI-15-0401

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Impact of the AYA HOPE Comorbidity Index on Assessing Health Care Service Needs and Health Status among Adolescents and Young Adults with Cancer

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Impact of the AYA HOPE Comorbidity Index on Assessing Health Care Service Needs and Health Status among Adolescents and Young Adults with Cancer

Xiao-Cheng Wu, Pinki K Prasad, Ian Landry, Linda C Harlan, Helen M Parsons, Charles F Lynch, Ashley W Smith, Ann S Hamilton, Theresa H M Keegan and AYA HOPE Study Collaborative Group

Cancer epidemiology, biomarkers & prevention, Vol.24(12), pp.1844-1849

12/2015

DOI: 10.1158/1055-9965.EPI-15-0401

PMCID: PMC4670595

PMID: 26420768

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Abstract

Existing comorbidity indices were not developed for adolescent and young adults (AYA) 15 to 39 years of age. The aim of this study was to assess impact of comorbidities on health care service needs and health status among AYA cancer survivors using the newly developed AYA HOPE comorbidity index in comparison with the existing indices. Data on comorbid conditions were obtained from medical records and service needs and health status were from a survey of AYA cancer survivors. Prevalence of comorbidities was based on the AYA HOPE index. Charlson and NCI indices were compared. Multivariable logistic regression was used. Of the 485 patients, 14.6% had ≥2 comorbidities based on the AYA HOPE Index. Prevalence of mental illness and obesity/overweight, which were not included in existing indices, were 8.2% and 5.8%, respectively. Prevalence of cardiovascular, endocrine, gastrointestinal, and neurologic conditions were higher with the AYA HOPE Index than the other two indices. Forty percent of AYA patients reported service needs, particularly for mental health services (25.2%) and support groups (17.7%). Having ≥2 comorbidities on the AYA index was associated with higher mental health service needs [OR, 2.05; 95% confidence interval (CI), 1.10-3.82] adjusting for demographic and clinical factors. Comorbidities were associated with fair/poor self-reported health status. The AYA HOPE Index is a more comprehensive comorbidity index for AYA cancer patients than existing indices, and the number of comorbidities is associated with service needs and health status. The AYA HOPE index could identify patients' additional service needs early in therapy.

United States - epidemiology

SEER Program

Age Factors

Comorbidity

Humans

Logistic Models

Male

Young Adult

Health Services Needs and Demand

Neoplasms - therapy

Adolescent

Quality of Life

Adult

Female

Health Status

Neoplasms - epidemiology

Details

Title: Subtitle: Impact of the AYA HOPE Comorbidity Index on Assessing Health Care Service Needs and Health Status among Adolescents and Young Adults with Cancer
Creators: Xiao-Cheng Wu - Department of Epidemiology, LSUHSC, New Orleans, Louisiana. xwu@lsuhsce.du
Pinki K Prasad - Department of Pediatric Hematology/Oncology, LSUSHC/Children's Hospital of New Orleans, New Orleans, Louisiana
Ian Landry - Department of Epidemiology, LSUHSC, New Orleans, Louisiana
Linda C Harlan - Applied Research Program, National Cancer Institute, Bethesda, Maryland
Helen M Parsons - University of Texas Health Science Center, San Antonio, Texas
Charles F Lynch - Department of Epidemiology, University of Iowa, Iowa City, Iowa
Ashley W Smith - Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, Maryland
Ann S Hamilton - Preventive Medicine, University of Southern California Norris Cancer Center, Los Angeles, California
Theresa H M Keegan - Department of Internal Medicine, Division of Hematology and Oncology, University of California, Davis, California
AYA HOPE Study Collaborative Group
Resource Type: Journal article
Publication Details: Cancer epidemiology, biomarkers & prevention, Vol.24(12), pp.1844-1849
DOI: 10.1158/1055-9965.EPI-15-0401
PMID: 26420768
PMCID: PMC4670595
NLM abbreviation: Cancer Epidemiol Biomarkers Prev
ISSN: 1055-9965
eISSN: 1538-7755
Publisher: United States
Grant note: HHSN261201300014I / PHS HHS HHSN261201300012I / NCI NIH HHS HHSN261201300005C / NCI NIH HHS HHSN261201300014C / NCI NIH HHS HHSN261201300016I / PHS HHS HHSN261201300020I / PHS HHS HHSN261201300012I / PHS HHS P30 CA086862 / NCI NIH HHS K07 CA175063 / NCI NIH HHS HHSN261201300004I / PHS HHS HHSN261201300005I / NCI NIH HHS HHSN261201300011I / NCI NIH HHS HHSN261201300004I / NCI NIH HHS HHSN261201300020C / NCI NIH HHS HHSN261201300005I / PHS HHS HHSN261201300016I / NCI NIH HHS HHSN261201300011I / PHS HHS HHSN261201300020I / NCI NIH HHS HHSN261201300011C / CCR NIH HHS HHSN261201000030C / NCI NIH HHS HHSN261201300016C / NCI NIH HHS
Language: English
Date published: 12/2015
Academic Unit: Epidemiology
Record Identifier: 9983996087802771

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