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Impact of the entry site on late outcome in acute Stanford type B aortic dissection
Journal article   Open access   Peer reviewed

Impact of the entry site on late outcome in acute Stanford type B aortic dissection

Tadashi Kitamura, Shinzo Torii, Norihiko Oka, Tetsuya Horai, Keiichi Itatani, Takeshi Yoshii, Yuki Nakamura, Miyuki Shibata, Tomoki Tamura, Haruna Araki, …
European journal of cardio-thoracic surgery, Vol.48(5), pp.655-661
11/01/2015
DOI: 10.1093/ejcts/ezu531
PMID: 25602060
url
https://doi.org/10.1093/ejcts/ezu531View
Published (Version of record) Open Access

Abstract

This study aimed to investigate whether the entry site of acute type B aortic dissection affects late outcomes. Inpatient and outpatient records were retrospectively reviewed. We identified 224 cases of acute type B aortic dissection between 1998 and 2013. Of these 224 patients, 168 were men and the age was 64.2 ± 12.6 (range 23-94) years, from which 130 presented with the entry at a location downstream of the distal aortic arch, 67 with the entry at the outer curvature of the distal aortic arch and 27 with the entry at the inner curvature. At the initial presentation, 127 patients had descending false lumen thrombosis. The 30-day mortality rate was 2%, and 8% of patients had malperfusion. The entry at the outer curvature was associated with a higher risk of 30-day mortality. Patients with the entry at a location downstream were significantly older, and had a higher chance for primarily thrombosed descending false lumen and a lower risk of malperfusion. At follow-up (6.0 ± 4.1 years), the actuarial survival rates were 97, 83 and 60%, freedoms from open aortic surgery were 96, 91 and 86%, aortic intervention were 73, 66 and 63% and aortic events were 71, 60 and 52% at 1, 5 and 10 years, respectively. Multivariate logistic regression analysis revealed that the outer curvature entry and maximum aortic diameter were correlated with open aortic surgery, aortic intervention and aortic events. Of the 127 patients with primarily thrombosed false lumen, the outer curvature entry was significantly correlated with aortic events. The primary entry at the outer curvature of the distal aortic arch, as well as the large aortic diameter, is associated with a higher risk of late open aortic surgery, aortic intervention and aortic events in acute type B aortic dissection. Thus, the entry site should be taken into consideration in the establishment of an appropriate treatment indication of type B aortic dissection.
 Adult Aged Aged, 80 and over Aneurysm, Dissecting - epidemiology Aneurysm, Dissecting - mortality Aneurysm, Dissecting - physiopathology Aortic Aneurysm - epidemiology Aortic Aneurysm - mortality Aortic Aneurysm - physiopathology Female Humans Male Middle Aged Retrospective Studies Young Adult

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