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Implementation of a single session psychotherapy intervention in primary care integrated behavioral health: a single-arm pilot study
Journal article   Open access   Peer reviewed

Implementation of a single session psychotherapy intervention in primary care integrated behavioral health: a single-arm pilot study

Anne I Roche, Brian L Straub, Emily B K Thomas, Hana-May Eadeh, Kyle A Schofield, Alanna M Chamberlain, Robert M Jacobson, Alisson N Lass, Jennifer Bailey, Kristin Vickers, …
BMC primary care
05/18/2026
DOI: 10.1186/s12875-026-03361-y
PMID: 42151859
url
https://doi.org/10.1186/s12875-026-03361-yView
Published (Version of record) Open Access

Abstract

Single-session interventions offer a novel approach to improving access to evidence-based mental health services using a population-based framework for delivery. The current single-arm pilot study aimed to assess the feasibility, acceptability, and preliminary effectiveness of a single-session intervention in Mayo Clinic's primary care Integrated Behavioral Health program.. Participants were recruited from Mayo Clinic's Integrated Behavioral Health program and participated in a therapist-delivered single-session therapy intervention in primary care. The intervention could be delivered by video or in-person and was based on acceptance and commitment therapy and solution-focused brief therapy principles. Descriptive statistics and 2-tailed paired sampled t-tests were used to examine outcomes. Less than 20% of the patients contacted expressed interest in the study; however, the majority who expressed interest and screened eligible completed the single-session therapy visit (N = 34). Acceptability was high, as indicated by study participants expressing generally high levels of satisfaction with the single visit. Participants experienced significant increases from pre- to post-intervention in readiness for change and in self-reported capacity to generate pathways toward goals. From pre-intervention to two-week follow-up, participants experienced significant reductions in depression and anxiety symptoms, significant increases in psychological flexibility and values progress, and significant decreases in values obstruction. Single-session interventions may be one helpful approach among a menu of stepped care options in primary care. Future work will benefit from ongoing exploration of the most appropriate processes for implementation of single-session interventions in primary care. The study is registered at ClinicalTrials.gov (NCT06347822); Registration Date: 03/29/2024.
Mental Health Psychological flexibility Acceptance and commitment therapy Integrated behavioral health Single-session intervention Primary care

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