Journal article
Implementation of a single session psychotherapy intervention in primary care integrated behavioral health: a single-arm pilot study
BMC primary care
05/18/2026
DOI: 10.1186/s12875-026-03361-y
PMID: 42151859
Abstract
Single-session interventions offer a novel approach to improving access to evidence-based mental health services using a population-based framework for delivery. The current single-arm pilot study aimed to assess the feasibility, acceptability, and preliminary effectiveness of a single-session intervention in Mayo Clinic's primary care Integrated Behavioral Health program..
Participants were recruited from Mayo Clinic's Integrated Behavioral Health program and participated in a therapist-delivered single-session therapy intervention in primary care. The intervention could be delivered by video or in-person and was based on acceptance and commitment therapy and solution-focused brief therapy principles. Descriptive statistics and 2-tailed paired sampled t-tests were used to examine outcomes.
Less than 20% of the patients contacted expressed interest in the study; however, the majority who expressed interest and screened eligible completed the single-session therapy visit (N = 34). Acceptability was high, as indicated by study participants expressing generally high levels of satisfaction with the single visit. Participants experienced significant increases from pre- to post-intervention in readiness for change and in self-reported capacity to generate pathways toward goals. From pre-intervention to two-week follow-up, participants experienced significant reductions in depression and anxiety symptoms, significant increases in psychological flexibility and values progress, and significant decreases in values obstruction.
Single-session interventions may be one helpful approach among a menu of stepped care options in primary care. Future work will benefit from ongoing exploration of the most appropriate processes for implementation of single-session interventions in primary care.
The study is registered at ClinicalTrials.gov (NCT06347822); Registration Date: 03/29/2024.
Details
- Title: Subtitle
- Implementation of a single session psychotherapy intervention in primary care integrated behavioral health: a single-arm pilot study
- Creators
- Anne I Roche - Mayo ClinicBrian L Straub - Mayo ClinicEmily B K Thomas - University of IowaHana-May Eadeh - Hennepin Healthcare Research InstituteKyle A Schofield - Mayo ClinicAlanna M Chamberlain - Mayo Clinic in FloridaRobert M Jacobson - Adolescent Health ClinicAlisson N Lass - Sanford HealthJennifer Bailey - Mayo Clinic Health SystemKristin Vickers - Mayo ClinicRhonda M Merwin - Duke UniversityCraig N Sawchuk - Mayo Clinic
- Resource Type
- Journal article
- Publication Details
- BMC primary care
- DOI
- 10.1186/s12875-026-03361-y
- PMID
- 42151859
- ISSN
- 2731-4553
- eISSN
- 2731-4553
- Publisher
- Springer Nature
- Grant note
- UL1 TR002377 / NCATS NIH HHS
- Language
- English
- Electronic publication date
- 05/18/2026
- Academic Unit
- Neurology; Psychological and Brain Sciences
- Record Identifier
- 9985164725202771
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