Journal article
Implications for driving based on the risk of seizures after ischaemic stroke
Journal of neurology, neurosurgery and psychiatry, Vol.95(9), pp.833-837
09/01/2024
DOI: 10.1136/jnnp-2024-333505
PMCID: PMC12056588
PMID: 38749674
Abstract
BackgroundIn addition to other stroke-related deficits, the risk of seizures may impact driving ability after stroke.MethodsWe analysed data from a multicentre international cohort, including 4452 adults with acute ischaemic stroke and no prior seizures. We calculated the Chance of Occurrence of Seizure in the next Year (COSY) according to the SeLECT2.0 prognostic model. We considered COSY<20% safe for private and <2% for professional driving, aligning with commonly used cut-offs.ResultsSeizure risks in the next year were mainly influenced by the baseline risk-stratified according to the SeLECT2.0 score and, to a lesser extent, by the poststroke seizure-free interval (SFI). Those without acute symptomatic seizures (SeLECT2.0 0–6 points) had low COSY (0.7%–11%) immediately after stroke, not requiring an SFI. In stroke survivors with acute symptomatic seizures (SeLECT2.0 3–13 points), COSY after a 3-month SFI ranged from 2% to 92%, showing substantial interindividual variability. Stroke survivors with acute symptomatic status epilepticus (SeLECT2.0 7–13 points) had the highest risk (14%–92%).ConclusionsPersonalised prognostic models, such as SeLECT2.0, may offer better guidance for poststroke driving decisions than generic SFIs. Our findings provide practical tools, including a smartphone-based or web-based application, to assess seizure risks and determine appropriate SFIs for safe driving.
Details
- Title: Subtitle
- Implications for driving based on the risk of seizures after ischaemic stroke
- Creators
- Kai Michael Schubert - University Hospital of ZurichGiulio Bicciato - University Hospital of ZurichLucia Sinka - Schulthess-KlinikLaura Abraira - Universitat Autònoma de BarcelonaEstevo Santamarina - Universitat Autònoma de BarcelonaJosé Álvarez-Sabín - Universitat Autònoma de BarcelonaCarolina Ferreira-Atuesta - Epilepsy SocietyMira Katan - University Hospital of BaselNatalie Scherrer - University Hospital of ZurichRobert Terziev - University Hospital of ZurichNico Döhler - Kantonsspital St. GallenBarbara Erdélyi-Canavese - Kantonsspital St. GallenAnsgar Felbecker - Kantonsspital St. GallenPhilip Siebel - Kantonsspital St. GallenMichael Winklehner - Johannes Kepler University of LinzTim J von Oertzen - Johannes Kepler University of LinzJudith N Wagner - Johannes Kepler University of LinzGian Luigi Gigli - University of UdineAnnacarmen Nilo - University of UdineFrancesco Janes - University of UdineGiovanni Merlino - University of UdineMariarosaria Valente - University of UdineMaría Paula Zafra-Sierra - Fundación Santa Fe de BogotáLuis Carlos Mayor-Romero - Universidad El BosqueJulian Conrad - Heidelberg UniversityS Evers - University of MünsterPiergiorgio Lochner - Saarland UniversityFrauke Roell - Saarland UniversityFrancesco Brigo - Krankenhaus MeranCarla Bentes - University of LisbonRita Peralta - Hospital de Santa MariaTeresa Pinho e Melo - Hospital de Santa MariaMark R Keezer - Stichting Epilepsie Instellingen NederlandJohn Sidney Duncan - Epilepsy SocietyJosemir W Sander - Sichuan UniversityBarbara Tettenborn - Kantonsspital St. GallenMatthias Koepp - Epilepsy SocietyMarian Galovic - University Hospital of Zurich
- Resource Type
- Journal article
- Publication Details
- Journal of neurology, neurosurgery and psychiatry, Vol.95(9), pp.833-837
- DOI
- 10.1136/jnnp-2024-333505
- PMID
- 38749674
- PMCID
- PMC12056588
- NLM abbreviation
- J Neurol Neurosurg Psychiatry
- ISSN
- 0022-3050
- eISSN
- 1468-330X
- Publisher
- BMJ Publishing Group Ltd
- Number of pages
- 5
- Language
- English
- Date published
- 09/01/2024
- Academic Unit
- Neurology
- Record Identifier
- 9985016422502771
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