Implications of Using Simplified Finite Element Meshes to Identify Material Parameters of Articular Cartilage

Nicole E. Szabo; Joshua E. Johnson; Marc J. Brouillette; Jessica E. Goetz

doi:10.1016/j.medengphy.2024.104200

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Implications of Using Simplified Finite Element Meshes to Identify Material Parameters of Articular Cartilage

Journal article

Peer reviewed

Implications of Using Simplified Finite Element Meshes to Identify Material Parameters of Articular Cartilage

Nicole E. Szabo, Joshua E. Johnson, Marc J. Brouillette and Jessica E. Goetz

Medical engineering & physics, Vol.131, 104200

06/2024

DOI: 10.1016/j.medengphy.2024.104200

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Abstract

•Finite element (FE) modeling can assist in deriving cartilage material parameters•2D-axisymmetric and flat 3D models simplify complex cartilage geometry•Porous viscohyperelastic material parameters vary with mesh simplification•Changes in material parameters translate to changes in computed tissue mechanics The objective of this work was to determine the effects of using simplified finite element (FE) mesh geometry in the process of performing reverse iterative fitting to estimate cartilage material parameters from in situ indentation testing. Six bovine tibial osteochondral explants were indented with sequential 5% step-strains followed by a 600 second hold while relaxation force was measured. Three sets of porous viscohyperelastic material parameters were estimated for each specimen using reverse iterative fitting of the indentation test with 1) 2D axisymmetric, 2) 3D idealized, and 3) 3D specimen-specific FE meshes. Variable material parameters were identified using the three different meshes, and there were no systematic differences, correlation to basic geometric features, nor distinct patterns of variation based on the type of mesh used. Implementing the three material parameter sets in a separate 3D FE model of 40% compressive strain produced differences in von Mises stresses and pore pressures up to 25% and 50%, respectively. Accurate material parameters are crucial in any FE model, and parameter differences influenced by idealized assumptions in initial material property determination have the potential to alter subsequent FE models in unpredictable ways and hinder the interpretation of their results.

Finite Element Analysis

Mechanics

Articular Cartilage

in situ indentation

Material Properties

Details

Title: Subtitle: Implications of Using Simplified Finite Element Meshes to Identify Material Parameters of Articular Cartilage
Creators: Nicole E. Szabo - Department of Orthopedics and Rehabilitation, University of Iowa, Iowa City, IA, 52242, USA
Joshua E. Johnson - University of Iowa
Marc J. Brouillette - University of Iowa
Jessica E. Goetz - Department of Orthopedics and Rehabilitation, University of Iowa, Iowa City, IA, 52242, USA
Resource Type: Journal article
Publication Details: Medical engineering & physics, Vol.131, 104200
Publisher: Elsevier Ltd
DOI: 10.1016/j.medengphy.2024.104200
ISSN: 1350-4533
eISSN: 1873-4030
Grant note: Peer Reviewed Medical Research Program Focused Program Award: W81XWH1810658
This work was supported by funding from the US Department of Defense Congressionally Directed Medical Research Programs. Specifically by the Peer Reviewed Medical Research Program Focused Program Award W81XWH1810658 (Principal Investigator Joseph Buckwalter IV).
Language: English
Electronic publication date: 06/2024
Academic Unit: Orthopedics and Rehabilitation; Roy J. Carver Department of Biomedical Engineering
Record Identifier: 9984652257702771

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