Implications of Weight and Body Mass Index for Plasma Donation and Health

Genna A Jerrard; Jing Liu; Rosemary C Case; Mahnaz Motevalli; Stephen G Bolton; Karen E King; John Beigel; J Brooks Jackson

doi:10.5402/2012/937585

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Implications of Weight and Body Mass Index for Plasma Donation and Health

Journal article

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Implications of Weight and Body Mass Index for Plasma Donation and Health

Genna A Jerrard, Jing Liu, Rosemary C Case, Mahnaz Motevalli, Stephen G Bolton, Karen E King, John Beigel and J Brooks Jackson

ISRN hematology, Vol.2012, pp.1-5

2012

DOI: 10.5402/2012/937585

PMCID: PMC3504381

PMID: 23209921

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Abstract

This study determined the percentage of potential plasma donors who could donate plasma in the 3 allowable plasma volume limit categories as specified by the Food and Drug Administration (FDA), as well as the association of the body mass index (BMI) of these individuals with age, blood pressure, oral temperature, and pulse. Of 315 plasma donors analyzed, 107 (34.0%) weighed between 110 and 149 lbs (50.0–67.7 kg), 89 (28.2%) weighed between 150 and174 lbs (68.2–79.1 kg), and 119 (37.8%) weighed >175 lbs (79.5 kg), theoretically allowing collection of an additional 101.4 liters (16% more plasma) from both heavier categories based on FDA standards for plasma donor quantities. BMI was positively associated with age, mean arterial pressure (MAP), and pulse (Pearson’sr=0.36, 0.24, and 0.18, resp.,Pvalues <0.05), but not with oral temperature. Average BMI for females was higher than for males (+1.8,P=0.01), and BMI for African Americans was higher than for White and Asian participants (+2.2and+5.1, resp.,Ps <0.05). A significant association was also found in the sex by race interaction with BMI (P=0.0004). Follow-up analyses suggested a significant difference in BMI by sex among African Americans, higher BMI among African American females than Asian and White males, and higher BMI among White females than African American males (Ps <0.05).

Details

Title: Subtitle: Implications of Weight and Body Mass Index for Plasma Donation and Health
Creators: Genna A Jerrard - Johns Hopkins Hospital, Carnegie 415, 600 North Wolfe Street, Baltimore, MD 21287, USA
Jing Liu - Johns Hopkins Hospital, Carnegie 415, 600 North Wolfe Street, Baltimore, MD 21287, USA
Rosemary C Case - Johns Hopkins Hospital, Carnegie 415, 600 North Wolfe Street, Baltimore, MD 21287, USA
Mahnaz Motevalli - Johns Hopkins Hospital, Carnegie 415, 600 North Wolfe Street, Baltimore, MD 21287, USA
Stephen G Bolton - Johns Hopkins Hospital, Carnegie 415, 600 North Wolfe Street, Baltimore, MD 21287, USA
Karen E King - Johns Hopkins Hospital, Carnegie 415, 600 North Wolfe Street, Baltimore, MD 21287, USA
John Beigel - Clinical Monitoring Research Program, SAIC-Frederick Inc., Frederick, MD 21702, USA, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH) Building 10, 8N234-C 10 Center Dr., MSC 1763, Bethesda, MD 20892-1763, USA
J Brooks Jackson - Johns Hopkins Hospital, Carnegie 415, 600 North Wolfe Street, Baltimore, MD 21287, USA
Resource Type: Journal article
Publication Details: ISRN hematology, Vol.2012, pp.1-5
DOI: 10.5402/2012/937585
PMID: 23209921
PMCID: PMC3504381
NLM abbreviation: ISRN Hematol
ISSN: 2090-4428
eISSN: 2090-4428
Language: English
Date published: 2012
Academic Unit: Pathology; VPMA - Administration
Record Identifier: 9984047994702771

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