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Improved Procedure for the Oxidative Cleavage of Olefins by OsO 4 −NaIO 4
Journal article   Peer reviewed

Improved Procedure for the Oxidative Cleavage of Olefins by OsO 4 −NaIO 4

Wensheng Yu, Yan Mei, Ying Kang, Zhengmao Hua and Zhendong Jin
Organic letters, Vol.6(19), pp.3217-3219
09/01/2004
DOI: 10.1021/ol0400342

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Abstract

(Chemical Equation Presented) Oxidative cleavage of olefins by OsO 4-NaIO4 sometimes suffers from low yields due to the formation of side products. It is found that the addition of 2,6-lutidine can suppress the side reactions and dramatically improve the yield of this classic reaction.

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