Journal article
Improving the temporal resolution of functional MR imaging using keyhole techniques
Magnetic resonance in medicine, Vol.35(6), pp.854-860
06/1996
DOI: 10.1002/mrm.1910350611
PMID: 8744013
Abstract
Using a keyhole technique, it is shown that the data acquisition rate of gradient-echo imaging for functional MRI (fMRI) studies can be increased substantially. The resulting enhancement of the temporal resolution of fMRIs was accomplished without modifying the hardware of a conventional MRI system. High spatial resolution fMRI images were first collected with conventional full k-space acquisition and image reconstruction. Using the same data set, simulation reconstruction using the keyhole principle and zero-padding were performed for comparison with the full k-space reconstruction. No significant changes were found for fMRI images generated from the keyhole technique with a data sharing profile of 50% of the k-space. As k-space data sharing profiles increased to 75 and 87.5%, the keyhole fMRI images began to show only modest changes in activation intensity and area compared with the standard images. In contrast, zero-padding fMRI images produced a significant disparity both in activation intensity and area relative to the truly high-resolution fMRI images. The keyhole technique's ability to retain the intensity and area of fMRI information, while substantially reducing acquisition time, makes it a promising method for fMRI studies.
Details
- Title: Subtitle
- Improving the temporal resolution of functional MR imaging using keyhole techniques
- Creators
- Jia-Hong Gao - Research Imaging Center, The University of Texas Health Science Center, San Antonio, TexasJinhu Xiong - Research Imaging Center, The University of Texas Health Science Center, San Antonio, TexasSong Lai - Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MissouriE. Mark Haacke - Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MissouriMarty G Woldorff - Research Imaging Center, The University of Texas Health Science Center, San Antonio, TexasJinqi Li - Research Imaging Center, The University of Texas Health Science Center, San Antonio, TexasPeter T Fox - Research Imaging Center, The University of Texas Health Science Center, San Antonio, Texas
- Resource Type
- Journal article
- Publication Details
- Magnetic resonance in medicine, Vol.35(6), pp.854-860
- Publisher
- Wiley Subscription Services, Inc., A Wiley Company
- DOI
- 10.1002/mrm.1910350611
- PMID
- 8744013
- ISSN
- 0740-3194
- eISSN
- 1522-2594
- Number of pages
- 7
- Language
- English
- Date published
- 06/1996
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering
- Record Identifier
- 9984083231002771
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