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In Vitro Pharmacodynamic Characteristics of Nystatin Including Time-Kill and Postantifungal Effect
Journal article   Open access   Peer reviewed

In Vitro Pharmacodynamic Characteristics of Nystatin Including Time-Kill and Postantifungal Effect

Shana M Gunderson, Holly Hoffman, Erika J Ernst, Michael A Pfaller and Michael E Klepser
Antimicrobial agents and chemotherapy, Vol.44(10), pp.2887-2890
10/01/2000
DOI: 10.1128/AAC.44.10.2887-2890.2000
PMCID: PMC90172
PMID: 10991881
url
https://europepmc.org/articles/pmc90172View
Published (Version of record) Open Access

Abstract

Four Candida albicans isolates and six non-albicans Candida isolates were evaluated by time-kill methods to characterize the relationship between nystatin concentrations, the rate and extent of fungicidal activity, and the postantifungal effect (PAFE). Against Candida species, nystatin exhibits concentration-dependent fungicidal activity and a pronounced PAFE.
Antifungal Agents Candida Nystatin Pharmacology

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