Journal article
In-hospital mortality and morbidity among extremely preterm infants in relation to maternal body mass index
Journal of perinatology, Vol.41(5), pp.1014-1024
05/01/2021
DOI: 10.1038/s41372-020-00847-0
PMCID: PMC8021608
PMID: 33024258
Abstract
Objective The objective of this paper is to compare in-hospital survival and survival without major morbidities in extremely preterm infants in relation to maternal body mass index (BMI). Methods This retrospective cohort study included extremely preterm infants (gestational age 22(0/7)-28(6/7)weeks). This study was conducted at National Institute of Child Health and Human Development Neonatal Research Network sites. Primary outcome was survival without any major morbidity. Results Maternal BMI data were available for 2415 infants. Survival without any major morbidity was not different between groups: 30.8% in the underweight/normal, 28.1% in the overweight, and 28.5% in the obese (P = 0.65). However, survival was lower in the obese group (76.5%) compared with overweight group (83.2%) (P = 0.02). Each unit increase in maternal BMI was associated with decreased odds of infant survival (P < 0.01). Conclusions Survival without any major morbidity was not associated with maternal obesity. An increase in maternal prepregnancy BMI was associated with decreased odds of infant survival.
Details
- Title: Subtitle
- In-hospital mortality and morbidity among extremely preterm infants in relation to maternal body mass index
- Creators
- Sanjay Chawla - Wayne State UniversityAbbot R. Laptook - Brown UniversityEmily A. Smith - RTI InternationalSylvia Tan - RTI InternationalGirija Natarajan - Wayne State UniversityMyra H. Wyckoff - The University of Texas Southwestern Medical CenterNamasivayam Ambalavanan - University of Alabama at BirminghamEdward F. Bell - University of IowaKrisa P. Van Meurs - Stanford UniversityDavid K. Stevenson - Stanford UniversityErika F. Werner - Brown UniversityRachel G. Greenberg - Duke UniversityAbhik Das - RTI InternationalSeetha Shankaran - Wayne State UniversityEunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Neonatal Research Network
- Resource Type
- Journal article
- Publication Details
- Journal of perinatology, Vol.41(5), pp.1014-1024
- DOI
- 10.1038/s41372-020-00847-0
- PMID
- 33024258
- PMCID
- PMC8021608
- NLM abbreviation
- J Perinatol
- ISSN
- 0743-8346
- eISSN
- 1476-5543
- Publisher
- Springer Nature
- Number of pages
- 11
- Grant note
- UG1HD27904; UG1HD21364; U10HD68284; UG1HD27853; UL1TR77; UG1HD40492; UL1TR1117; UL1TR1111; UG1HD27851; UL1TR454; U10HD27856; UL1TR6; UG1HD87229; U10HD68278 / Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
- Language
- English
- Date published
- 05/01/2021
- Academic Unit
- Stead Family Department of Pediatrics; Neonatology
- Record Identifier
- 9984353935602771
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