In vitro orientation of male Schistosoma mansoni to extracts derived from female schistosomes

J. E Childs; DJAMSHID Shirazian; J. B Gloer; E. L Schiller

doi:10.1007/BF01022378

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In vitro orientation of male Schistosoma mansoni to extracts derived from female schistosomes

Journal article

Peer reviewed

In vitro orientation of male Schistosoma mansoni to extracts derived from female schistosomes

J. E Childs, DJAMSHID Shirazian, J. B Gloer and E. L Schiller

Journal of chemical ecology, Vol.12(8), pp.1729-1738

1986

DOI: 10.1007/BF01022378

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Abstract

Chemical orientation of adult male Schistosoma mansoni was studied during cultivation in vitro. Directional preference was assessed in culture vessels marked with compass coordinates by the application of circular statistics for determining clustering and orientation to a predicted direction. Organic solvent extracts of fresh female schistosomes and supernatant fluids from 72-hr cultures of female parasites were tested for potential chemotactic activity. Analysis showed significant (P < 0.05) directional preference and clustering of male worms towards test compounds at all time periods (24, 48, and 72 hr) with one mixture of female extracts and at one of three time periods with a second female extract. Male worms did not respond to ecdysone, cholesterol, or solvent controls by orienting in predicted direction, although clustering was observed on two of 12 occasions. These results indicate the presence of a chemoattractant compound(s) in female extracts. © 1986 Plenum Publishing Corporation.

Infectious Diseases

Tropical Medicine

Biological and medical sciences

Diseases caused by trematodes

Fundamental and applied biological sciences. Psychology

Helminthic diseases

Invertebrates

Medical sciences

Nemathelminthia. Plathelmintha

Parasitic diseases

Physiology. Development

Schistosomiases

Details

Title: Subtitle: In vitro orientation of male Schistosoma mansoni to extracts derived from female schistosomes
Creators: J. E Childs - Johns Hopkins univ., dep. immunology infectious diseases, Baltimore MD 21205, United States
DJAMSHID Shirazian - Johns Hopkins univ., dep. immunology infectious diseases, Baltimore MD 21205, United States
J. B Gloer - Johns Hopkins univ., dep. immunology infectious diseases, Baltimore MD 21205, United States
E. L Schiller - Johns Hopkins univ., dep. immunology infectious diseases, Baltimore MD 21205, United States
Resource Type: Journal article
Publication Details: Journal of chemical ecology, Vol.12(8), pp.1729-1738
Publisher: Springer
DOI: 10.1007/BF01022378
ISSN: 0098-0331
eISSN: 1573-1561
Language: English
Date published: 1986
Academic Unit: Chemistry
Record Identifier: 9984216697602771

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