Journal article
In vivo and in vitro biocompatibility tests of endodontic cements
Bulletin du Groupement international pour la recherche scientifique en stomatologie & odontologie, Vol.35(1-2), pp.13-21
03/01/1992
PMID: 1477511
Abstract
The major goal endodontic therapy has been achieved by condensing filling materials into the root canal. It's not uncommon to find excess material into the periapical tissue. It therefore becomes obligatory to use fillings materials that have acceptable biocompatibility. The purpose of this investigation was to obtain a "toxicity profile" of some endodontics materials and to compare our observations to results present in literature. The gutta-percha and five endodontic filling cements were tested "in vivo" and "in vitro". The in vivo biocompatibility involved the placement of the test material in 10 mm. Teflon tubes with an outer diameter of 1.3 mm which were implanted subcutaneously into rats. The implants were left in situ for periods of 30 and 90 days. The "hemolysis test" is designed for "in vitro" evaluations. The histological examination showed different intensity and extent cellular responses. In some cases severe infiltration of inflammatory cell and areas with necrotic were seen. At conclusion, the endodontics material evaluated showed slight, moderate and severe reactions; therefore a different pattern in tissue response.
Details
- Title: Subtitle
- In vivo and in vitro biocompatibility tests of endodontic cements
- Creators
- L FonziV KaistasA GasparoniM BelliL Capezzuoli
- Resource Type
- Journal article
- Publication Details
- Bulletin du Groupement international pour la recherche scientifique en stomatologie & odontologie, Vol.35(1-2), pp.13-21
- PMID
- 1477511
- ISSN
- 0250-4693
- Language
- French
- Date published
- 03/01/1992
- Academic Unit
- Oral Pathology, Radiology and Medicine; Dental Clinic Administration
- Record Identifier
- 9984367649202771
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