Inbreeding Depression in Genotypically Matched Diploid and Tetraploid Maize

Hong Yao; Sanvesh Srivastava; Nathan Swyers; Fangpu Han; Rebecca W Doerge; James A Birchler

doi:10.3389/fgene.2020.564928

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Inbreeding Depression in Genotypically Matched Diploid and Tetraploid Maize

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Inbreeding Depression in Genotypically Matched Diploid and Tetraploid Maize

Hong Yao, Sanvesh Srivastava, Nathan Swyers, Fangpu Han, Rebecca W Doerge and James A Birchler

Frontiers in genetics, Vol.11, pp.564928-564928

11/30/2020

DOI: 10.3389/fgene.2020.564928

PMCID: PMC7734256

PMID: 33329701

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Abstract

The genetic and molecular basis of heterosis has long been studied but without a consensus about mechanism. The opposite effect, inbreeding depression, results from repeated self-pollination and leads to a reduction in vigor. A popular explanation for this reaction is the homozygosis of recessive, slightly deleterious alleles upon inbreeding. However, extensive studies in alfalfa indicated that inbreeding between diploids and autotetraploids was similar despite the fact that homozygosis of alleles would be dramatically different. The availability of tetraploid lines of maize generated directly from various inbred lines provided the opportunity to examine this issue in detail in perfectly matched diploid and tetraploid hybrids and their parallel inbreeding regimes. Identical hybrids at the diploid and tetraploid levels were inbred in triplicate for seven generations. At the conclusion of this regime, F1 hybrids and selected representative generations (S1, S3, S5, S7) were characterized phenotypically in randomized blocks during the same field conditions. Quantitative measures of the multiple generations of inbreeding provided little evidence for a distinction in the decline of vigor between the diploids and the tetraploids. The results suggest that the homozygosis of completely recessive, slightly deleterious alleles is an inadequate hypothesis to explain inbreeding depression in general.

Genetics

heterosis

inbreeding depression

maize

progressive heterosis

tetraploid

Details

Title: Subtitle: Inbreeding Depression in Genotypically Matched Diploid and Tetraploid Maize
Creators: Hong Yao - University of Missouri
Sanvesh Srivastava - University of Iowa
Nathan Swyers - University of Missouri
Fangpu Han - University of Missouri
Rebecca W Doerge - Carnegie Mellon University
James A Birchler - University of Missouri
Resource Type: Journal article
Publication Details: Frontiers in genetics, Vol.11, pp.564928-564928
DOI: 10.3389/fgene.2020.564928
PMID: 33329701
PMCID: PMC7734256
NLM abbreviation: Front Genet
ISSN: 1664-8021
eISSN: 1664-8021
Publisher: Frontiers Media S.A
Language: English
Date published: 11/30/2020
Academic Unit: Statistics and Actuarial Science
Record Identifier: 9984257630102771

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