Incidence and Clinical Characteristics of Infantile Conjunctivitis in a Western Population

Cole E. Bothun; Sasha A. Mansukhani; Timothy T. Xu; Tina M. Hendricks; David O. Hodge; Brian G. Mohney

doi:10.1016/j.ajo.2022.04.008

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Incidence and Clinical Characteristics of Infantile Conjunctivitis in a Western Population

Journal article

Peer reviewed

Incidence and Clinical Characteristics of Infantile Conjunctivitis in a Western Population

Cole E. Bothun, Sasha A. Mansukhani, Timothy T. Xu, Tina M. Hendricks, David O. Hodge and Brian G. Mohney

American journal of ophthalmology, Vol.241, pp.145-148

09/01/2022

DOI: 10.1016/j.ajo.2022.04.008

PMCID: PMC10441006

PMID: 35469786

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https://pmc.ncbi.nlm.nih.gov/articles/PMC10441006/pdf/nihms-1913658.pdfView

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Abstract

OBJECTIVE To describe the incidence and clinical characteristics of conjunctivitis in the first year of life. DESIGN Population-based cohort study. PARTICIPANTS All infant (≤12 months of age) residents of Olmsted County, Minnesota, diagnosed with conjunctivitis from January 1, 2005, through December 31, 2014. METHODS The medical records of all potential cases identified by the Rochester Epidemiology Project database were reviewed. MAIN OUTCOME MEASURES Incidence rate and clinical features of infantile conjunctivitis. RESULTS A total of 2175 infants were diagnosed during the 10-year period, yielding an incidence of 10,422 per 100,000 children or approximately 1 in 10 infants by 1 year of age. The mean age at diagnosis was 4.9 months (range, 1 day–12 months), and 1001 (46.0%) were female. Both eyes were involved in 1180 (54.3%), the right eye alone in 506 (23.3%), and 489 (22.5%) in the left. Five hundred seventy-six (26.5%) of the 2175 were diagnosed at ≤30 days of life, from which topical cultures were obtained in 111 (19.7%). Only 36 (32.4%) of the cultures showed bacterial agents, with Chlamydia present in 3. Treatment for infantile conjunctivitis, where recorded, included topical antibiotics in 523 (90.8%) and simple observation in 47 (8.2%). CONCLUSIONS Conjunctivitis in the first year of life occurred in approximately 10% of infants in this population-based cohort. More than half involved both eyes, one-quarter were identified in the first 30 days of life, and sight-threatening infectious agents were rare.

Ophthalmology

Life Sciences & Biomedicine

Science & Technology

Details

Title: Subtitle: Incidence and Clinical Characteristics of Infantile Conjunctivitis in a Western Population
Creators: Cole E. Bothun - Mayo Clinic
Sasha A. Mansukhani - Mayo Clinic
Timothy T. Xu - Mayo Clinic
Tina M. Hendricks - Mayo Clinic
David O. Hodge - Mayo Clinic in Florida
Brian G. Mohney - Mayo Clinic
Resource Type: Journal article
Publication Details: American journal of ophthalmology, Vol.241, pp.145-148
DOI: 10.1016/j.ajo.2022.04.008
PMID: 35469786
PMCID: PMC10441006
NLM abbreviation: Am J Ophthalmol
ISSN: 0002-9394
eISSN: 1879-1891
Publisher: Elsevier
Number of pages: 4
Grant note: AG 058738 / National Institute on Aging (NIA); United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute on Aging (NIA) Mayo Clinic Research Committee
Language: English
Date published: 09/01/2022
Academic Unit: Ophthalmology and Visual Sciences
Record Identifier: 9984697642802771

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