Journal article
Incident Apathy During the First Year After Stroke and Its Effect on Physical and Cognitive Recovery
The American journal of geriatric psychiatry, Vol.21(9), pp.848-854
09/01/2013
DOI: 10.1016/j.jagp.2013.03.012
PMID: 23831176
Abstract
Objective: This prospective study examined the course of cognitive, physical, and social impairment among patients who developed apathy during the first year after stroke. Methods: Patients diagnosed with apathy (N = 23) were compared with patients who had no apathy (N = 33) at initial, 3, 6, 9, and 12 months after stroke for severity of global cognitive impairment as measured by Mini-Mental State Examination, severity of impairment in activities of daily living (ADLs) as measured by Functional Independence Measure, and severity of impairment in social functioning as measured by Social Functioning Exam. Results: A total of 41.1% of patients met diagnostic criteria for apathy during the first year after stroke. The mean time from stroke to onset of apathy was 3.8 (3.3 SD) months and the mean duration was 5.6 (2.3 SD) months. Using a linear mixed model, after controlling for age, initial severity of impairment, and major depression, patients in the apathy group had significantly less recovery in cognition (t(149) = -2.06;p = 0.0411) and ADLs (t(104) = -3.37; p = 0.0011) during the first year after stroke compared with nonapathic patients. Conclusion: Apathy is common after stroke and leads to less recovery in cognition and ADLs over the first year after stroke compared with similar nonapathic patients.
Details
- Title: Subtitle
- Incident Apathy During the First Year After Stroke and Its Effect on Physical and Cognitive Recovery
- Creators
- Katsunaka Mikami - Tokai UniversityRicardo E. Jorge - Roy J. and Lucille A. Carver College of MedicineDavid J. Moser - Roy J. and Lucille A. Carver College of MedicineMijin Jang - Roy J. and Lucille A. Carver College of MedicineRobert G. Robinson - Roy J. and Lucille A. Carver College of Medicine
- Resource Type
- Journal article
- Publication Details
- The American journal of geriatric psychiatry, Vol.21(9), pp.848-854
- Publisher
- Elsevier
- DOI
- 10.1016/j.jagp.2013.03.012
- PMID
- 23831176
- ISSN
- 1064-7481
- eISSN
- 1545-7214
- Number of pages
- 7
- Grant note
- R01 MH 065134 / National Institutes of Health; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA R01MH065134 / NATIONAL INSTITUTE OF MENTAL HEALTH; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Institute of Mental Health (NIMH) Tokai University, Kanagawa, Japan
- Language
- English
- Date published
- 09/01/2013
- Academic Unit
- Psychiatry; Medicine Administration
- Record Identifier
- 9984280836302771
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