Increase in diabetes among urban Alaska Native people in the Alaska EARTH follow-up study: A call for prediabetes screening, diagnosis, and referral for intervention

Kathryn R Koller; Gretchen E Day; Vanessa Y Hiratsuka; Julie A Beans; Sarah H Nash; Diana G Redwood; Jianhui Zhu; Barbara V Howard; Jason G Umans

doi:10.1016/j.diabres.2020.108357

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Increase in diabetes among urban Alaska Native people in the Alaska EARTH follow-up study: A call for prediabetes screening, diagnosis, and referral for intervention

Journal article

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Increase in diabetes among urban Alaska Native people in the Alaska EARTH follow-up study: A call for prediabetes screening, diagnosis, and referral for intervention

Kathryn R Koller, Gretchen E Day, Vanessa Y Hiratsuka, Julie A Beans, Sarah H Nash, Diana G Redwood, Jianhui Zhu, Barbara V Howard and Jason G Umans

Diabetes research and clinical practice, Vol.167, pp.108357-108357

09/2020

DOI: 10.1016/j.diabres.2020.108357

PMCID: PMC7530054

PMID: 32745696

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https://www.ncbi.nlm.nih.gov/pmc/articles/7530054View

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Abstract

This study estimates incidence of diabetes (DM) and pre-DM relative to DM risk factors among relatively healthy Alaska Native and American Indian (henceforth AN) adults living in urban south central Alaska. Methods: Baseline (2004–2006) and follow-up (2014–2017) surveys, blood samples, and medical chart review data were collected from AN adults living in south central Alaska. We analyzed associations between prevalent risk factors and incident DM and pre-DM using Cox proportional hazards and used multivariable models to identify independent predictors for both DM and pre-DM. Results: Among 379 participants with follow-up data, overall DM incidence was 16.5/1,000 PY; overall pre-DM incidence was 77.6/1,000 PY, with marked differences between men and women. Prevalent cardiometabolic risk factors also varied with greater amounts of overweight in men and greater amounts of obesity in women. Controlling for age and sex, obesity, abdominal adiposity, pre-DM, and metabolic syndrome independently increased DM risk. Conclusion: Health care providers of AN populations must seize the opportunity to screen, refer, and treat individuals with pre-DM and other modifiable DM risk factors prior to DM diagnosis if we are to alter the epidemiologic course of disease progression in this urban AN population.

Alaska Native

American Indian

Cardiometabolic risk factors

Cohort study

Diabetes

Prediabetes

Details

Title: Subtitle: Increase in diabetes among urban Alaska Native people in the Alaska EARTH follow-up study: A call for prediabetes screening, diagnosis, and referral for intervention
Creators: Kathryn R Koller - Clinical and Research Services, Alaska Native Tribal Health Consortium, Anchorage, AK, United States
Gretchen E Day - Clinical and Research Services, Alaska Native Tribal Health Consortium, Anchorage, AK, United States
Vanessa Y Hiratsuka - Research Department, Southcentral Foundation, Anchorage, AK, United States
Julie A Beans - Research Department, Southcentral Foundation, Anchorage, AK, United States
Sarah H Nash - Alaska Native Epidemiology Center, Alaska Native Tribal Health Consortium, Anchorage, AK, United States
Diana G Redwood - Alaska Native Epidemiology Center, Alaska Native Tribal Health Consortium, Anchorage, AK, United States
Jianhui Zhu - Medstar Health Research Institute, Hyattsville, MD, United States
Barbara V Howard - Medstar Health Research Institute, Hyattsville, MD, United States
Jason G Umans - Medstar Health Research Institute, Hyattsville, MD, United States
Resource Type: Journal article
Publication Details: Diabetes research and clinical practice, Vol.167, pp.108357-108357
DOI: 10.1016/j.diabres.2020.108357
PMID: 32745696
PMCID: PMC7530054
NLM abbreviation: Diabetes Res Clin Pract
ISSN: 0168-8227
eISSN: 1872-8227
Publisher: Elsevier B.V
Grant note: DOI: 10.13039/100000054, name: National Cancer Institute, award: CA88958, CA96095; DOI: 10.13039/100005239, name: Indian Health Service; DOI: 10.13039/100000057, name: National Institute of General Medical Sciences; DOI: 10.13039/100000002, name: National Institutes of Health; DOI: 10.13039/100000057, name: NIGMS, award: U261IHS0084
Language: English
Date published: 09/2020
Academic Unit: Epidemiology; Center for Social Science Innovation
Record Identifier: 9984214676302771

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